Protein S deficiency
MONDO:0002304Protein S deficiency is a disorder that causes abnormal blood clotting. When someone bleeds, the blood begins a complicated series of rapid chemical reactions involving proteins called blood coagulation factors to stop the bleeding. Other proteins in the blood, such as protein S, usually regulate these chemical reactions to prevent excessive clotting. When protein S is missing (deficient), clotting may not be regulatednormally and affected individuals have an increased risk of forming a blood clot called a thrombosis. People at risk to haveprotein S deficiency are those with an individual or family history of multiple blood clots in the veins. Treatment may include taking medication known as blood thinners to decrease the chance of developing a blood clot.
Also known as: Protein S deficiency, Protein S deficiency disease
6 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsSub-types
Broader categories
-
Battlefield plasma goes civil: can a powder save trauma victims?
Disease control CompletedThis study tested a freeze-dried plasma product that can be mixed with water in 6 minutes, avoiding the long thaw time of standard plasma. It included 42 trauma patients with severe bleeding who needed blood transfusions. The goal was to see if faster plasma delivery could improv…
Phase: PHASE3 • Sponsor: University Hospital, Lille • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
-
Peanut power: could a simple supplement improve elderly health?
Disease control CompletedThis study tested whether a peanut-based nutritional supplement could improve health in adults aged 60 and older living in peri-urban Ghana. Over 12 weeks, 81 participants either took the supplement daily or served as a control group. Researchers measured weight, blood pressure, …
Phase: PHASE1 • Sponsor: University of Ghana • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
-
New combo therapy aims to free ventilator patients faster
Disease control CompletedThis study tested whether adding a high-protein diet, core muscle exercises, and neuromuscular electrical stimulation helps patients who have been on a breathing machine for over 21 days wean off it. One hundred participants received these treatments alongside usual care. The mai…
Phase: NA • Sponsor: Chang Gung Memorial Hospital • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC
-
Plasma donation study: frequent Donors' health under the microscope
Knowledge-focused CompletedThis study looked at whether donating plasma more often affects protein levels, inflammation, and mental health in male blood donors. 120 men were split into three groups: one donated plasma three times every two weeks, another every two weeks, and a third donated whole blood eve…
Phase: NA • Sponsor: Sykehuset Innlandet HF • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC