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Prion disease

MONDO:0005429

A transmissible disease that is caused by a protein that is able to induce abnormal folding of normal cellular proteins, leading to characteristic spongiform brain changes, which are associated with neuronal loss without an inflammatory response. Such disorders have typically long incubation periods, but are then generally rapidly progressive and are uniformly fatal.

Also known as: spongiform encephalopathy

11 clinical trials for this condition and its sub-types.

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Sub-types

Inherited Creutzfeldt-Jakob disease (5) Creutzfeldt Jacob disease (4) Fatal familial insomnia (4) Gerstmann-Straussler-Scheinker syndrome (1) Acquired Creutzfeldt-Jakob disease (0) Familial Alzheimer-like prion disease (0) Huntington disease-like 1 (0) Iatrogenic Creutzfeldt-Jakob disease (0) Kuru (0) PrP systemic amyloidosis (0) Scrapie (0) Spongiform encephalopathy with neuropsychiatric features (0) Sporadic Creutzfeldt-Jakob disease (0) Sporadic fatal insomnia (0) Variant Creutzfeldt-Jakob disease (0)

Broader categories

Disease (680) Infectious disease (282) Nervous system disorder (231) Brain disorder (125) Central nervous system disorder (107) Human disease (14) Central nervous system infectious disorder (10) Infectious disorder of the nervous system (4) Disease by body system or component (0) Disease by etiologic mechanism (0)
Trials to join now! 5 Not yet recruiting 2 Not yet finished but already full! 2 Completed 2
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