Prinzmetal angina
MONDO:0006021A syndrome typically consisting of angina (cardiac chest pain) at rest that occurs in cycles. It is caused by vasospasm, a narrowing of the coronary arteries caused by contraction of the smooth muscle tissue in the vessel walls rather than directly by atherosclerosis (buildup of fatty plaque and hardening of the arteries). For a portion of patients Prinzmetal's angina may be a manifestation of vasospastic disorder and is associated with migraine, Raynaud's phenomenon or aspirin-induced asthma.
Also known as: angina inversa, variant angina
77 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
-
Heart spasm study tests vitamins and statins – but ends early
Disease control TerminatedThis study looked at whether long-term treatment with vitamin C+E and statins could reduce artery spasms and plaque buildup in people with variant angina, a type of chest pain. The trial planned to enroll 320 adults aged 30 and older, but it was terminated early. The main goal wa…
Phase: PHASE4 • Sponsor: Seoul National University Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:25 UTC
-
Painkiller may weaken heart drug during stent surgery
Knowledge-focused TerminatedThis study tested whether fentanyl, a painkiller used during heart stent procedures, reduces the effectiveness of ticagrelor, a blood thinner given to prevent clots. Researchers compared crushed versus whole ticagrelor pills in 45 patients. The trial was stopped early, so results…
Phase: PHASE4 • Sponsor: The Guthrie Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC