Primary angle-closure glaucoma
MONDO:0001868An angle-closure glaucoma characterized by closure of the anterior chamber angle by an intrinsic defect such that aqueous outflow is blocked and the intraocular pressure becomes inappropriately elevated leading to optic nerve damage and visual field loss. Primary angle-closure glaucoma has symptom progressive peripheral vision loss, decreased vision, and pain, redness, and headache in acute cases. Primary angle closure glaucoma can be caused by anatomically narrow angle, defects in the trabecular meshwork, and iris abnormalities. Primary angle-closure glaucoma has a strong genetic component.
25 clinical trials for this condition and its sub-types, 14 tagged with Primary angle-closure glaucoma itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Part of
Sub-types of Primary angle-closure glaucoma
-
Chronic closed-angle glaucoma 7 trials
-
Acute closed-angle glaucoma 1 trial
-
Interval angle-closure glaucoma 0 trials
-
New eye implant aims to ease glaucoma pressure
Disease control OngoingThis study tests a small implant placed inside the eye to help drain fluid and lower pressure in people with open-angle or narrow-angle glaucoma. It is for adults whose eye pressure is not well controlled with eye drops. The main goal is to see if the implant safely reduces press…
Sponsor: Ciliatech • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
-
Laser showdown: where to zap the iris for better glaucoma control?
Disease control OngoingThis study tests two different spots (temporal vs inferior) for a YAG laser iridotomy in people with angle-closure glaucoma. Each patient gets one spot in each eye, and doctors track pressure, symptoms, and complications over six months. The goal is to find which location is safe…
Sponsor: Isfahan University of Medical Sciences • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC