Pleural disorder
MONDO:0002037A non-neoplastic or neoplastic disorder that affects the pleura. Representative examples include pleural infection, pleural mesothelioma, and pleural solitary fibrous tumor.
Also known as: disease of pleura, disease or disorder of pleura, disorder of pleura, pleura disease, pleura disease or disorder, pleural disorder, pleural disorders, non-neoplastic pleural disease
177 clinical trials for this condition and its sub-types, 15 tagged with Pleural disorder itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Pleural disorder
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Pleural neoplasm 5 trials · 97 incl. sub-types
5 sub-types
- Pleural mesothelioma 28 trials · 86 incl. sub-types Sub-types →
- Pleural cancer 9 trials · 83 incl. sub-types Sub-types →
- Benign neoplasm of pleura 0 trials Sub-types →
- Neurilemmoma of the pleura 0 trials
- Pleural solitary fibrous tumor 0 trials Sub-types →
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Pneumothorax 35 trials · 45 incl. sub-types
5 sub-types
- Familial spontaneous pneumothorax 13 trials
- Hemopneumothorax 2 trials
- Spontaneous tension pneumothorax 1 trial
- Catamenial pneumothorax 0 trials
- Tuberculous pneumothorax 0 trials
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Pleural empyema 20 trials
1 sub-type
- Tuberculous empyema 0 trials
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Pleurisy 2 trials · 9 incl. sub-types
2 sub-types
- Pleural tuberculosis 7 trials Sub-types →
- Pleuropneumonia 0 trials
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Congenital chylothorax 0 trials
Most studied deeper sub-types
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Can a simple saline flush boost treatment for stubborn lung infections?
Disease control Recruiting nowThis trial tests whether adding saline irrigation to standard care helps clear infected fluid in the chest cavity, a condition called retained pleural infection. Adults with this infection who already have a chest tube will either receive standard treatment alone or standard trea…
Phase 2 • Sponsor: Beth Israel Deaconess Medical Center • Aim: Disease control
Last updated Aug 30, 2026 00:00 UTC
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Can a simple saline wash clear stubborn chest infections?
Disease control Recruiting nowThis pilot trial tests whether a new irrigation device can safely and effectively wash out retained pleural infections using saline. The study enrolls 10 people who have a chest tube in place but cannot receive standard enzyme therapy. Researchers will use bedside ultrasound to m…
Sponsor: Beth Israel Deaconess Medical Center • Aim: Disease control
Last updated Aug 29, 2026 00:00 UTC
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New ultrasound score could revolutionize lung disease diagnosis
Diagnosis Recruiting nowThis study is testing a new ultrasound measurement called the Lung Sliding Index (LSI) to see if it can help doctors tell apart different lung diseases, such as COPD, pneumonia, and pulmonary edema. Researchers will measure LSI in 700 adults with various lung conditions and healt…
Sponsor: Assiut University • Aim: Diagnosis
Last updated Jun 27, 2026 12:26 UTC
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New microscope technique aims to sharpen diagnosis of mysterious chest fluid
Diagnosis Recruiting nowThis study tests whether using a special microscope (confocal laser endomicroscopy) during a chest camera procedure can better diagnose unexplained pleural disease. About 158 adults with fluid around the lungs that standard tests couldn't diagnose will be randomly assigned to get…
Sponsor: China-Japan Friendship Hospital • Aim: Diagnosis
Last updated Jun 27, 2026 12:07 UTC
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Could a single daily dose beat a double for lung infection treatment?
Symptom relief Recruiting nowThis study tests whether giving medication once a day through a chest tube works as well as giving it twice a day for people with serious infections around the lungs. Participants are adults already in the hospital with a chest tube draining infected fluid. They will be randomly …
Phase 4 • Sponsor: University of North Carolina, Chapel Hill • Aim: Symptom relief
Last updated Jun 27, 2026 12:35 UTC