Peptic ulcer disease
MONDO:0004247A digestive system disease characterized by discontinuation in the inner lining of the gastrointestinal (GI) tract because of gastric acid secretion or pepsin.
Also known as: acute peptic ulcer with haemorrhage, acute peptic ulcer with haemorrhage and perforation, acute peptic ulcer without haemorrhage and without perforation, peptic ulcer
67 clinical trials for this condition and its sub-types, 26 tagged with Peptic ulcer disease itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Peptic ulcer disease
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Peptic esophagitis 24 trials
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Gastric ulcer 13 trials
1 sub-type
- Gastroduodenitis 0 trials
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Duodenal ulcer 7 trials
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Gastrojejunal ulcer 6 trials
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Active peptic ulcer disease 3 trials
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Peptic ulcer perforation 3 trials
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Which works better for h. pylori? triple vs quadruple therapy showdown
Disease control CompletedThis study tested two different 14-day drug combinations to treat Helicobacter pylori, a bacteria that causes stomach inflammation and ulcers. Over 750 adults were randomly assigned to either a triple therapy (omeprazole, amoxicillin, clarithromycin) or a quadruple therapy (omepr…
Phase 4 • Sponsor: Azfar Farogh • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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Battle of the bacteria: which drug combo wins against resistant h. pylori?
Disease control CompletedThis study tested two different drug combinations in 782 people with H. pylori infection that was resistant to the antibiotic clarithromycin. One group received a triple therapy with a proton pump inhibitor, amoxicillin, and metronidazole, while the other received a quadruple the…
Sponsor: Kangdong Sacred Heart Hospital • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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No more tubes? swallowable capsule could revolutionize stomach acid testing
Diagnosis CompletedThis study tests a new, less invasive way to measure stomach acid using a small wireless capsule (SmartPill) that patients swallow. It compares the capsule's accuracy to the standard method, which involves a tube placed through the nose into the stomach. The study includes health…
Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) • Aim: Diagnosis
Last updated Sep 02, 2026 00:00 UTC
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Can a new acid blocker match the standard for protecting NSAID Users' stomachs?
Prevention CompletedResearchers are testing whether tegoprazan 25 mg works as well as lansoprazole 15 mg at preventing stomach and duodenal ulcers in people who take NSAID pain relievers for at least six months. The trial enrolls adults aged 60 or older, or younger adults with a history of such ulce…
Phase 3 • Sponsor: HK inno.N Corporation • Aim: Prevention
Last updated Sep 16, 2026 00:00 UTC