Osteonecrosis
MONDO:0005380A none disease characterized by death of bone tissue due to a lack of blood supply.
Also known as: bone necrosis, ischaemic bone disease, ischemic bone disease, osteonecrosis
224 clinical trials for this condition and its sub-types, 59 tagged with Osteonecrosis itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
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Sub-types of Osteonecrosis
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Avascular necrosis 80 trials · 141 incl. sub-types
3 sub-types
- Primary avascular necrosis 0 trials · 39 incl. sub-types Sub-types →
- Secondary avascular necrosis 1 trial · 38 incl. sub-types Sub-types →
- Dysbaric osteonecrosis 0 trials
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Osteonecrosis of genetic origin 0 trials · 102 incl. sub-types
12 sub-types
- Familial avascular necrosis of femoral head 20 trials · 39 incl. sub-types Sub-types →
- Scheuermann disease 24 trials
- Osteochondritis dissecans 20 trials
- Gaucher disease type I 12 trials
- Legg-Calve-Perthes disease 9 trials
- Dihydropyrimidine dehydrogenase deficiency 3 trials
- Epiphysiolysis of the hip 3 trials
- Hereditary antithrombin deficiency 3 trials
- Thiemann disease, familial form 0 trials
- Hereditary thrombophilia due to congenital histidine-rich (poly-L) glycoprotein deficiency 0 trials
- Pseudohypoparathyroidism type 1C 0 trials
- Short stature and advanced bone age, with or without early-onset osteoarthritis and/or osteochondritis dissecans 0 trials
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Osteochondrosis 8 trials · 46 incl. sub-types
11 sub-types
- Scheuermann disease 24 trials
- Legg-Calve-Perthes disease 9 trials
- Osgood-Schlatter disease 5 trials
- Dihydropyrimidine dehydrogenase deficiency 3 trials
- Kienbock disease 1 trial
- Osteochondritis of tarsal/metatarsal bone 1 trial
- Freiberg disease 0 trials
- Sinding-Larsen-Johansson disease 0 trials
- Thiemann disease, familial form 0 trials
- Medial condensing osteitis of the clavicle 0 trials
- Panner disease 0 trials
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Osteoradionecrosis 14 trials · 15 incl. sub-types
1 sub-type
- Osteoradionecrosis of the mandible 5 trials
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Dieterich disease 1 trial
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Kummell disease 1 trial
Most studied deeper sub-types
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Oxygen chamber therapy put to the test for dozens of diseases
Disease control Not yet recruitingThis study will test hyperbaric oxygen therapy (HBOT) — breathing pure oxygen in a pressurized chamber — for over 30 conditions, including long COVID, Crohn's disease, frostbite, and multiple sclerosis. Researchers will track 100 patients to see if HBOT improves their quality of …
Phase 4 • Sponsor: Jay C. Buckey Jr. • Aim: Disease control
Last updated Sep 11, 2026 00:00 UTC
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Oxygen therapy may boost hip procedure for bone death
Disease control Not yet recruitingThis study tests whether adding hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) to a standard hip procedure (core decompression with bone marrow cells) can reduce pain in people with early-stage avascular necrosis of the hip. The trial will enroll 400 p…
Sponsor: Yale University • Aim: Disease control
Last updated Jul 03, 2026 00:00 UTC
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New surgical tool may ease recovery for jaw bone disease patients
Symptom relief Not yet recruitingThis study compares two surgical techniques for treating medication-related osteonecrosis of the jaw (MRONJ), a condition where jawbone dies due to certain drugs. Thirty-four adults with stage 1 or 2 MRONJ will be randomly assigned to receive either traditional rotary instrument …
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Symptom relief
Last updated Jun 27, 2026 07:51 UTC