New surgical tool may ease recovery for jaw bone disease patients
NCT ID NCT06622421
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study compares two surgical techniques for treating medication-related osteonecrosis of the jaw (MRONJ), a condition where jawbone dies due to certain drugs. Thirty-four adults with stage 1 or 2 MRONJ will be randomly assigned to receive either traditional rotary instrument surgery or newer piezoelectric surgery. The main goal is to see which method causes less discomfort after surgery, with follow-up over 12 months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Piezoelectric surgery device
- What this could lead to
- If successful, this could show that piezoelectric surgery causes less pain and faster recovery for patients with jaw bone death caused by certain medications.
- What could go wrong
- This is a small, early-stage trial with only 34 participants, so results may not apply to everyone. The main goal is comfort, not a cure, and the condition can still return.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Catholic University
Roma, 00168, Italy
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Other studies related to the condition(s) this trial covers.