Oral cavity cancer
MONDO:0005515A primary or metastatic malignant neoplasm involving the oral cavity. The majority are squamous cell carcinomas.
Also known as: cancer of oral cavity, malignant mouth neoplasm, malignant mouth tumor, malignant mouth tumour, malignant neoplasm of mouth, malignant neoplasm of oral cavity, malignant neoplasm of the mouth, malignant oral cavity neoplasm
3140 clinical trials for this condition and its sub-types, 42 tagged with Oral cavity cancer itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Oral cavity cancer
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Oral cavity carcinoma 16 trials · 202 incl. sub-types
9 sub-types
- Oral cavity squamous cell carcinoma 141 trials · 156 incl. sub-types Sub-types →
- Salivary gland carcinoma 26 trials · 36 incl. sub-types Sub-types →
- Oral cavity carcinoma in situ 5 trials Sub-types →
- Tongue carcinoma 4 trials
- Carcinoma of lip 0 trials · 2 incl. sub-types Sub-types →
- Carcinoma of hard palate 1 trial
- Carcinoma of soft palate 1 trial
- Intraoral basal cell carcinoma 0 trials
- Oral cavity mucoepidermoid carcinoma 0 trials Sub-types →
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Salivary gland cancer 62 trials · 81 incl. sub-types
3 sub-types
- Salivary gland carcinoma 26 trials · 36 incl. sub-types Sub-types →
- Major salivary gland cancer 7 trials · 16 incl. sub-types Sub-types →
- Malignant tumor of minor salivary gland 0 trials Sub-types →
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Tongue cancer 26 trials · 35 incl. sub-types
2 sub-types
- Tongue squamous cell carcinoma 9 trials · 13 incl. sub-types Sub-types →
- Tongue carcinoma 4 trials
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Lip cancer 12 trials · 15 incl. sub-types
3 sub-types
- Carcinoma of lip 0 trials · 2 incl. sub-types Sub-types →
- Lower lip cancer 1 trial
- Upper lip cancer 0 trials
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Cheek mucosa cancer 1 trial · 2 incl. sub-types
1 sub-type
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Gingival cancer 1 trial · 2 incl. sub-types
2 sub-types
- Upper gum cancer 2 trials
- Lower gum cancer 0 trials
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Retromolar area cancer 1 trial
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Hard palate cancer 0 trials · 1 incl. sub-types
1 sub-type
- Carcinoma of hard palate 1 trial
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Soft palate cancer 0 trials · 1 incl. sub-types
2 sub-types
- Carcinoma of soft palate 1 trial
- Uvula cancer 0 trials
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Oral rhabdomyosarcoma 0 trials
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Vestibule of mouth cancer 0 trials
1 sub-type
Most studied deeper sub-types
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Could less radiation be better? new trial spares healthy neck tissue
Disease control OngoingThis phase 2 trial tests whether it is safe to skip radiation on one or both sides of the neck that show no signs of cancer after surgery. The goal is to reduce side effects like dry mouth and trouble swallowing without increasing the chance of cancer returning. The study include…
Phase 2 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jul 31, 2026 00:00 UTC
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New study tests safer pain relief for oral cancer patients
Symptom relief By invitation onlyThis study compares two pain management strategies for adults with oral cancer who have moderate to severe pain. One group receives the opioid tramadol, while the other gets a combination of pregabalin and naproxen sodium. Over 7 days, researchers measure pain reduction, side eff…
Sponsor: Mayo Hospital Lahore • Aim: Symptom relief
Last updated Jun 27, 2026 12:37 UTC
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Amazonian tree oil may soothe radiation mouth sores in cancer patients
Symptom relief OngoingThis early-phase study tests whether a mouthwash made from copaiba, a natural oil from the Amazon, can safely help prevent and treat painful mouth sores caused by radiation therapy in 20 adults with head and neck cancer. Researchers will find the highest safe dose and measure pai…
Phase 1 • Sponsor: Instituto Nacional de Cancer, Brazil • Aim: Symptom relief
Last updated Jun 27, 2026 12:28 UTC
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Natural mouthwash aimed to soothe radiation mouth sores, but study never started
Symptom relief CancelledThis study planned to test a mouthwash made from copaíba oil, a natural resin, to prevent and treat painful mouth sores (oral mucositis) in people with oral cancer undergoing radiation. The trial was set to include 40 patients, half using the copaíba mouthwash and half a placebo,…
Phase 2 • Sponsor: Instituto Nacional de Cancer, Brazil • Aim: Symptom relief
Last updated Jun 27, 2026 12:05 UTC
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AI messages aim to curb drinking in cancer survivors
Knowledge-focused By invitation onlyThis study tests whether AI-generated messages can change how cancer survivors think about alcohol and cancer risk. About 850 adults who have had certain cancers and currently drink alcohol will view different messages. Researchers will measure changes in their beliefs about canc…
Sponsor: University of Miami • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:36 UTC