Open-angle glaucoma
MONDO:0005338Chronic outflow obstruction of the eye's drainage canals that can lead to increased internal eye pressure and optic nerve damage.
Also known as: POAG, glaucoma, primary open angle, open angle glaucoma, pigmentary glaucoma, primary open angle glaucoma
168 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsSub-types
Broader categories
-
Glaucoma supplement trial fizzles: MEMOPTIC study halted early
Disease control TerminatedThis study tested whether a daily tablet called MEMOPTIC (containing citicoline, magnesium, and Ginkgo biloba) could help preserve vision in people with open-angle glaucoma when added to their usual eye-pressure-lowering treatments. The trial planned to follow 15 patients for two…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Disease control
Last updated Jun 27, 2026 13:05 UTC
-
Eye drop combo study for glaucoma halted early
Disease control TerminatedThis study tested two different combinations of eye drops to lower eye pressure in people with open-angle glaucoma or ocular hypertension. The goal was to see which combination worked better over 90 days. The study was stopped early and included 28 participants.
Phase: PHASE4 • Sponsor: Laboratorios Sophia S.A de C.V. • Aim: Disease control
Last updated Jun 27, 2026 12:31 UTC
-
Glaucoma device Follow-Up study ends early
Disease control TerminatedThis study looked at the long-term safety and effectiveness of the STREAMLINE® Surgical System in people with open-angle glaucoma. It included 17 patients who had already taken part in an earlier trial of the same device. The goal was to see if the device continued to safely lowe…
Sponsor: New World Medical, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:03 UTC
-
Glaucoma supplement trial halted early – no clear results
Disease control TerminatedThis study tested whether a daily dietary supplement called GlaucoCetin could improve vision in people with open-angle glaucoma who already had some vision loss. Only 12 participants were enrolled before the trial was terminated early. The supplement contained a mix of ingredient…
Phase: NA • Sponsor: Wills Eye • Aim: Disease control
Last updated Jun 27, 2026 08:05 UTC
-
VR headsets tested as a possible treatment for blindness
Disease control TerminatedThis study tested whether using a virtual reality headset for one-hour sessions could help regenerate damaged optic nerves and improve vision in people with glaucoma or other retinal diseases. The idea came from promising results in rodents. However, the trial was terminated earl…
Phase: NA • Sponsor: Stanford University • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
-
Glaucoma pressure fight: new device vs laser – which wins?
Disease control TerminatedThis study tested a new device (VISCO™360) against a standard laser treatment to lower eye pressure in adults with open-angle glaucoma. Only 29 people took part before the study was stopped early. The goal was to see which method works better and is safer for controlling the dise…
Phase: NA • Sponsor: Sight Sciences, Inc. • Aim: Disease control
Last updated Jun 27, 2026 07:57 UTC
-
Glaucoma device showdown ends early: only 10 patients enrolled
Disease control TerminatedThis study aimed to compare two surgical devices—the OMNI system and the iStent inject—for lowering eye pressure in people with open-angle glaucoma who already had cataract surgery. The trial was terminated early and only enrolled 10 participants, so results are limited. Both dev…
Phase: NA • Sponsor: Sight Sciences, Inc. • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
-
Glaucoma Drug-Eluting contact lens trial halted after single patient
Disease control TerminatedThis study tested a special contact lens that slowly releases the glaucoma drug latanoprost, aiming to replace daily eye drops. Only one person enrolled before the study was stopped early. The goal was to check safety and whether the lens could lower eye pressure, but no conclusi…
Phase: PHASE1 • Sponsor: Massachusetts Eye and Ear Infirmary • Aim: Disease control
Last updated Jun 27, 2026 07:54 UTC
-
Glaucoma implant trial halted early – what we know
Disease control TerminatedThis study tested a new medical device called Supraflow v1.3, which is implanted in the eye to help drain fluid and lower pressure in people with open-angle glaucoma. The trial included 22 patients whose eye pressure was not controlled with medication. However, the study was term…
Phase: NA • Sponsor: Ciliatech • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC
-
Tiny drops, big hope? study tests nanodropper for glaucoma
Symptom relief TerminatedThis study tested whether a device called Nanodropper, which makes smaller eye drops, works as well as standard eye drops for lowering eye pressure in people with glaucoma or ocular hypertension. The study enrolled 16 adults who already used a common glaucoma drop. The goal was t…
Phase: NA • Sponsor: University of California, San Francisco • Aim: Symptom relief
Last updated Jun 27, 2026 09:10 UTC