Nongerminomatous germ cell tumor
MONDO:0021656A term that refers to teratoma, embryonal carcinoma, yolk sac tumor, choriocarcinoma, or mixed forms of these tumors.
Also known as: Nongerminomatous germ cell tumor, Nongerminomatous germ cell tumor Including central nervous system, Nongerminomatous germ cell tumour, Nongerminomatous germ cell tumour Including central nervous system, non-dysgerminomatous germ cell tumor, non-dysgerminomatous germ cell tumour, non-germinomatous germ cell tumor, non-germinomatous germ cell tumour
1465 clinical trials for this condition and its sub-types, 12 tagged with Nongerminomatous germ cell tumor itself.
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Sub-types of Nongerminomatous germ cell tumor
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Extragonadal non-dysgerminomatous germ cell tumor 0 trials · 21 incl. sub-types
4 sub-types
- Extragonadal nonseminomatous germ cell tumor 5 trials · 19 incl. sub-types Sub-types →
- Central nervous system nongerminomatous germ cell tumor 2 trials Sub-types →
- Extragonadal teratoma 0 trials · 1 incl. sub-types Sub-types →
- Mediastinum teratoma 1 trial Sub-types →
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Teratoma 6 trials · 10 incl. sub-types
13 sub-types
- Gonadal teratoma 0 trials · 3 incl. sub-types Sub-types →
- Malignant teratoma 1 trial · 3 incl. sub-types Sub-types →
- Immature teratoma 2 trials Sub-types →
- Sacrococcygeal teratoma 2 trials
- Central nervous system teratoma 0 trials · 1 incl. sub-types Sub-types →
- Cystic teratoma 0 trials · 1 incl. sub-types Sub-types →
- Mature teratoma 0 trials · 1 incl. sub-types Sub-types →
- Mediastinum teratoma 1 trial Sub-types →
- Adult teratoma 0 trials Sub-types →
- Fallopian tube teratoma 0 trials
- Gastric teratoma 0 trials Sub-types →
- Nasopharyngeal teratoma 0 trials
- Teratoma with malignant transformation 0 trials Sub-types →
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Malignant non-dysgerminomatous germ cell tumor of ovary 1 trial · 2 incl. sub-types
5 sub-types
- Immature ovarian teratoma 1 trial · 2 incl. sub-types Sub-types →
- Ovarian embryonal carcinoma 1 trial Sub-types →
- Ovarian yolk sac tumor 1 trial Sub-types →
- Gestational ovarian choriocarcinoma 0 trials
- Polyembryoma of the ovary 0 trials
Most studied deeper sub-types
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New hope for advanced cancers? first human trial launches
Disease control Recruiting nowThis early-stage study is testing a new drug called BGB-B2033, alone or with other drugs, in people with advanced liver, stomach, or lung cancers. The goal is to see if it is safe and how well it works. About 392 participants will take part.
Phase 1/2 • Sponsor: BeOne Medicines • Aim: Disease control
Last updated Sep 18, 2026 00:00 UTC
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Major trial tests gentler chemo for germ cell tumors
Disease control Recruiting nowThis phase 3 trial studies two approaches for germ cell tumors. For low-risk patients whose tumor has been removed, doctors will monitor them closely instead of giving chemotherapy. For standard-risk patients whose cancer has spread, the trial compares two chemotherapy drugs—carb…
Phase 3 • Sponsor: Children's Oncology Group • Aim: Disease control
Last updated Aug 27, 2026 00:00 UTC
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Could a simple pill keep relapsed testicular cancer at bay?
Disease control Recruiting nowThis study is for people with relapsed germ cell tumors (a type of cancer often in the testicles or ovaries) who have already had high-dose chemotherapy and a stem cell transplant. It tests whether taking a daily oral chemotherapy drug called etoposide for a while after treatment…
Phase 2 • Sponsor: Nabil Adra • Aim: Disease control
Last updated Jun 27, 2026 12:30 UTC
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New drug duo aims to keep relapsed germ cell cancer in check
Disease control Recruiting nowThis study tests whether taking two drugs (zanzalintinib and oral etoposide) after high-dose chemotherapy can help keep relapsed germ cell tumors from growing. About 38 adults whose cancer has not been cured by standard treatments will participate. The goal is to see if this comb…
Phase 1/2 • Sponsor: Indiana University • Aim: Disease control
Last updated Jun 27, 2026 07:58 UTC
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Robots and dye could spare testicular cancer patients unnecessary treatment
Diagnosis Recruiting nowThis study tests a new, less invasive way to check if testicular cancer has spread. Doctors inject a dye into the testicle, then use a robot to find and remove the first lymph node that drains the tumor. The goal is to see if this method is accurate enough to replace more extensi…
Sponsor: Heinrich-Heine University, Duesseldorf • Aim: Diagnosis
Last updated Jun 26, 2026 17:11 UTC
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Can a simple injection save your hearing during cancer treatment?
Symptom relief Recruiting nowThis early-stage trial tests whether adding Pedmark to standard cisplatin chemotherapy can prevent hearing loss in men with metastatic testicular cancer. About 80% of patients currently develop hearing damage from cisplatin. Pedmark works by neutralizing harmful molecules that ca…
Phase 1 • Sponsor: City of Hope Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 12:09 UTC
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Blood test aims to spot hidden cancer cells in 9 tumor types
Knowledge-focused Recruiting nowThis study is looking for certain cells in the blood of people with 9 types of advanced cancers that have spread. Researchers will take one blood sample from each of 450 participants before they start a new treatment. They will use two different lab methods to see if they can fin…
Sponsor: Institut Claudius Regaud • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC