Neutropenia
MONDO:0001475A decrease in the number of neutrophils found in the blood.
Also known as: neutropenia, neutropenic disorder
58 clinical trials for this condition and its sub-types, 34 tagged with Neutropenia itself.
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Sub-types of Neutropenia
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Constitutional neutropenia 2 trials · 28 incl. sub-types
13 sub-types
- Chediak-Higashi syndrome 9 trials
- Severe congenital neutropenia 5 trials · 8 incl. sub-types Sub-types →
- Barth syndrome 5 trials
- WHIM syndrome 1 4 trials
- Glycogen storage disease Ib 3 trials
- Cohen syndrome 1 trial
- Griscelli syndrome type 2 1 trial
- Cyclic hematopoiesis 1 trial
- Hermansky-Pudlak syndrome 2 0 trials
- Lichtenstein syndrome 0 trials
- Neutropenia-monocytopenia-deafness syndrome 0 trials
- Poikiloderma with neutropenia 0 trials
- Primary immunodeficiency syndrome due to p14 deficiency 0 trials
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ELANE-related neutropenia 0 trials · 1 incl. sub-types
2 sub-types
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Neonatal alloimmune neutropenia 0 trials
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Transient neonatal neutropenia 0 trials
Most studied deeper sub-types
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New combo aims to tame Chemo's worst side effect in deadly lung cancer
Disease control Recruiting nowThis Phase 2 trial tests whether adding trilaciclib to the chemotherapy drug lurbinectedin can reduce severe neutropenia (a dangerous drop in white blood cells) in people with small cell lung cancer that has spread. About 30 participants will receive both drugs intravenously. The…
Phase 2 • Sponsor: UNC Lineberger Comprehensive Cancer Center • Aim: Disease control
Last updated Sep 21, 2026 17:00 UTC
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New drug aims to boost immune cells in rare blood disorder
Disease control Recruiting nowThis Phase 3 study tests whether the drug mavorixafor can reduce serious infections and increase neutrophil levels in people with chronic neutropenia—a condition where the body doesn't make enough infection-fighting white blood cells. About 176 participants will receive either ma…
Phase 3 • Sponsor: X4 Pharmaceuticals • Aim: Disease control
Last updated Aug 08, 2026 00:03 UTC
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Can a new protein drug shield kids with cancer from dangerous infections?
Disease control Recruiting nowThis trial tests whether a new drug called albipagrastim alfa can prevent severe neutropenia (dangerously low white blood cell counts) in children with sarcoma who are receiving chemotherapy. The drug is designed to stimulate the body's production of infection-fighting neutrophil…
Phase 2 • Sponsor: Qilu Pharmaceutical Co., Ltd. • Aim: Disease control
Last updated Jul 26, 2026 00:00 UTC
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Can a safer dose of an old drug shield vulnerable children from deadly fungal infections?
Disease control Recruiting nowThis trial tests whether a low dose of the antifungal drug liposomal amphotericin B can prevent invasive fungal infections in children aged 3 to 17 who have prolonged neutropenia (very low white blood cell counts) after cancer treatment or stem cell transplant. The drug is given …
Sponsor: Haikou Affiliated Hospital of Central South University Xiangya School of Medicine • Aim: Disease control
Last updated Jul 26, 2026 00:00 UTC
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New study tests herbal vs standard drug for chemo side effect in breast cancer
Disease control Recruiting nowThis study compares two treatments—Shengbai Oral Liquid (a herbal remedy) and Leucogen tablets (a standard drug)—for moderate neutropenia (low white blood cells) caused by anti-tumor drugs in breast cancer patients. Sixty participants will be randomly assigned to receive one trea…
Phase 4 • Sponsor: Hongxia Wang • Aim: Disease control
Last updated Jun 27, 2026 12:32 UTC
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New Single-Shot drug may protect kids on chemo from dangerous infections
Disease control Recruiting nowThis study tests whether a single injection of Telpegfilgrastim works better than daily Filgrastim shots to prevent fever and low white blood cells in children and young adults (ages 6-24) with solid tumors receiving strong chemotherapy. About 132 participants will receive either…
Phase 2 • Sponsor: Cancer Institute and Hospital, Chinese Academy of Medical Sciences • Aim: Disease control
Last updated Jun 27, 2026 12:30 UTC
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New hope: drug may shield breast cancer patients from dangerous side effect
Disease control Recruiting nowThis phase II trial tests whether taking leucogen alongside standard ribociclib therapy can prevent severe neutropenia (dangerously low white blood cell counts) in women with early-stage hormone-positive breast cancer. About 94 participants will receive the combination and be mon…
Phase 2 • Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University • Aim: Disease control
Last updated Jun 27, 2026 12:26 UTC
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New antibiotic could shield blood cancer patients from deadly infections
Disease control Recruiting nowThis study is for people with blood cancers like leukemia who are getting chemotherapy or a stem cell transplant, which can cause very low white blood cell counts (neutropenia) for over a week. The goal is to see if the antibiotic eravacycline can prevent serious bacterial infect…
Phase 2 • Sponsor: West Virginia University • Aim: Disease control
Last updated Jun 27, 2026 12:07 UTC
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Can a single drug boost blood counts and delay cancer in High-Risk patients?
Disease control Recruiting nowThis study tests the drug luspatercept in 50 adults with clonal cytopenias of uncertain significance (CCUS), a condition where low blood cell counts increase the risk of developing blood cancers like leukemia. Participants receive injections every three weeks for up to 48 weeks. …
Phase 2 • Sponsor: Weill Medical College of Cornell University • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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New drug aims to shield cancer patients from chemo side effect
Disease control Recruiting nowThis study tests whether a drug called mecapegfilgrastim can safely prevent moderate-to-severe myelosuppression (low blood cell counts) caused by chemotherapy and radiation for lung or esophageal cancer. About 30 adults aged 18-75 will receive the drug alongside their standard ca…
Phase 2 • Sponsor: Affiliated Hospital of Nantong University • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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Can a Low-Dose antifungal shield vulnerable patients from deadly fungal infections?
Prevention Recruiting nowThis study looks at whether a low dose of the antifungal drug liposomal amphotericin B can prevent serious fungal infections in adults with blood cancers or who have had stem cell transplants and have a prolonged low white blood cell count (neutropenia). The trial enrolls 30 pati…
Sponsor: Haikou Affiliated Hospital of Central South University Xiangya School of Medicine • Aim: Prevention
Last updated Aug 15, 2026 00:00 UTC
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New drug may shield cancer patients from dangerous infection risk
Prevention Recruiting nowThis real-world study looks at whether a drug called mecapegfilgrastim can prevent neutropenia (a low white blood cell count) in cancer patients after chemotherapy, radiation, or immunotherapy. The study will follow 200 adults with solid tumors who are at high or moderate risk of…
Sponsor: Hebei Medical University Fourth Hospital • Aim: Prevention
Last updated Jun 27, 2026 09:07 UTC
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Allergy drug and supplement face off in battle against cancer treatment bone pain
Symptom relief Recruiting nowThis study tests two oral medications—diosmin-hesperidin (a flavonoid supplement) and loratadine (an allergy drug)—to prevent bone pain caused by G-CSF, a drug that boosts white blood cells in blood cancer patients. Researchers will compare each drug alone and in combination agai…
Sponsor: Alexandria University • Aim: Symptom relief
Last updated Jun 27, 2026 14:02 UTC
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New registry aims to unlock secrets of rare bone marrow disease
Knowledge-focused Recruiting nowThis study is creating a registry for people with Shwachman-Diamond Syndrome (SDS) or similar conditions. Researchers will collect medical records and biological samples from up to 5,000 participants to understand how the disease progresses and what treatments work best. The goal…
Sponsor: Boston Children's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
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Cancer patients may soon check their blood at home, skipping unnecessary hospital trips
Knowledge-focused Recruiting nowThis study explores whether cancer patients can safely monitor their own blood counts at home during chemotherapy. About 265 participants from Denmark, Poland, and Germany will test a home monitoring device for several cycles. The goal is to reduce unnecessary hospital visits, lo…
Sponsor: Pomeranian Medical University Szczecin • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC