Neonatal anemia

This phase 2 trial tests whether personalized dosing of epoetin alfa—a lab-made hormone that boosts red blood cell production—can reduce or eliminate the need for blood transfusions in very low birth weight premature infants with neonatal anemia. Researchers will study how the dr…

This study tests whether giving blood transfusions more liberally (when hemoglobin drops to 9 g/dL) versus more restrictively (when it drops to 7.5 g/dL) reduces death and serious complications like heart attack, stroke, or kidney injury in patients aged 70 and older undergoing n…

This trial compared two approaches for twin-to-twin transfusion syndrome (TTTS) stage 1: immediate laser surgery versus careful observation. 179 pregnant women with TTTS stage 1 and favorable conditions took part. The goal was to see which strategy leads to better survival and br…

This study tested whether red blood cells from umbilical cord blood are safe and work as well as standard adult donor blood for transfusions in extremely preterm infants (born before 28 weeks). 41 babies received small transfusions, and researchers monitored their vital signs, ox…

This study followed 179 children aged 4 to 16 who were born from twin pregnancies complicated by twin-to-twin transfusion syndrome (TTTS). Researchers checked their heart function, blood pressure, kidney health, and blood sugar control to see if the condition during pregnancy cau…

This study explored whether low hemoglobin (anemia) is linked to an enlarged heart (cardiomegaly) in children up to 18 years old. Researchers used chest X-rays and echocardiograms to check for heart enlargement in 56 anemic children. The goal was to better understand how anemia a…

This study looked at 201 very premature babies born before 31 weeks to see how often they received blood transfusions that went beyond French guidelines. Researchers found that many transfusions were given even when not recommended, possibly due to the babies' fragile health. The…