Nasopharyngeal carcinoma, susceptibility to, 1
MONDO:0011775Any nasopharyngeal carcinoma in which the cause of the disease is a mutation in the TP53 gene.
Also known as: TP53 nasopharyngeal carcinoma, nasopharyngeal carcinoma 1, nasopharyngeal carcinoma caused by mutation in TP53, nasopharyngeal carcinoma, somatic, nasopharyngeal carcinoma, susceptibility to, 1, NPC, Npca, nasopharyngeal cancer
55 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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New chemo combo shows promise for common throat cancer in southern china
Disease control CompletedThis study tested a new combination of chemotherapy drugs (nab-paclitaxel, cisplatin, and fluorouracil) given before standard chemoradiation in 60 people with advanced nasopharyngeal cancer. The goal was to see if this approach could shrink tumors and improve survival. The trial …
Phase: PHASE2 • Sponsor: Guangxi Medical University • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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Can a pill shield ears from chemo damage?
Prevention CompletedThis study tests whether the drug SENS-401 can prevent hearing loss caused by cisplatin, a common chemotherapy. Adults with cancer who are scheduled to receive cisplatin take SENS-401 before, during, and after treatment. Hearing is measured with a standard test to see if the drug…
Phase: PHASE2 • Sponsor: Sensorion • Aim: Prevention
Last updated Jul 04, 2026 00:00 UTC
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Can a registry help more families get tested for cancer genes?
Knowledge-focused CompletedThis study looked at 545 people with hereditary cancer syndromes and their relatives. It compared the usual method of asking patients to share testing information with family members to a new method where a registry also sends reminders. The goal was to see if the registry-aided …
Phase: NA • Sponsor: National Cancer Centre, Singapore • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:03 UTC
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Digital tool helps families navigate Kids' cancer risk
Knowledge-focused CompletedThis study tested whether digital care plans and text message reminders help families of children with cancer predisposition syndromes better understand their child's condition. Researchers enrolled 177 parents and measured changes in knowledge and how acceptable the digital tool…
Phase: NA • Sponsor: Children's Hospital of Philadelphia • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:37 UTC
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Immunotherapy side effects under the microscope: new study monitors autoantibodies
Knowledge-focused CompletedThis completed study followed 183 cancer patients starting checkpoint inhibitor therapy to see how often they develop autoantibodies—proteins that can mistakenly attack the body's own tissues. Researchers collected blood samples to track changes in several types of autoantibodies…
Sponsor: CHU de Reims • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Mailed DNA tests could help families catch cancer early
Knowledge-focused CompletedThis study looked at whether mailing at-home genetic testing kits to relatives of people with hereditary cancer gene variants could increase the number of relatives who get tested. Researchers compared this approach to usual care in 108 participants. The goal was to see if making…
Phase: NA • Sponsor: University of Texas Southwestern Medical Center • Aim: Knowledge-focused
Last updated Jun 26, 2026 13:30 UTC