Can a pill shield ears from chemo damage?
NCT ID NCT05628233
First seen Jul 02, 2026 · Last updated Jul 02, 2026
Summary
This study tests whether the drug SENS-401 can prevent hearing loss caused by cisplatin, a common chemotherapy. Adults with cancer who are scheduled to receive cisplatin take SENS-401 before, during, and after treatment. Hearing is measured with a standard test to see if the drug protects against damage.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
SENS-401 (R-Azasetron Besylate)
What this could lead to
If it works, this could offer a way to protect hearing during cisplatin chemotherapy without reducing cancer treatment effectiveness.
What could go wrong
This is a small Phase 2a trial, so results may not confirm benefit. The drug could also have side effects or fail to prevent hearing loss.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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Other studies related to the condition(s) this trial covers.
Contacts and locations
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Locations
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Hôpital Henri Mondor
Créteil, 94010, France