Multifocal motor neuropathy
MONDO:0018979Multifocal motor neuropathy (MMN) is a rare acquired immune-mediatedneuropathy characterized clinically by a purely motor deficit with conduction block and asymmetric multifocal weakness, fasciculations, and cramping.
Also known as: MMN, MMNCB, multifocal motor neuropathy with conduction block
13 clinical trials for this condition and its sub-types.
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New drug aims to replace IVIg for nerve disease
Disease control OngoingThis study tests if a new drug, empasiprubart, works as well as standard IVIg treatment for adults with multifocal motor neuropathy (MMN), a condition that causes muscle weakness. About 154 people who have responded to IVIg in the past will be randomly assigned to receive either …
Phase: PHASE3 • Sponsor: argenx • Aim: Disease control
Last updated Jun 27, 2026 12:35 UTC
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New drug aims to keep rare nerve disease in check long-term
Disease control OngoingThis study is a long-term follow-up for people with multifocal motor neuropathy, a rare condition that causes muscle weakness. It tests the safety and effectiveness of a drug called ARGX-117, given intravenously. The trial includes 51 adults who previously took part in an earlier…
Phase: PHASE2 • Sponsor: argenx • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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Major study launches to unravel the Real-World impact of rare nerve disease
Knowledge-focused OngoingThis study follows about 413 adults with multifocal motor neuropathy (MMN) over time to learn how the disease progresses and affects daily life. Researchers will collect information on symptoms, quality of life, and healthcare use during regular doctor visits. No experimental tre…
Sponsor: argenx • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC