New drug could reduce need for infusions in nerve disorder
NCT ID NCT06537999
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This Phase 2 trial tests a drug called claseprubart (DNTH103) in 36 adults with multifocal motor neuropathy, a rare nerve condition that causes muscle weakness. Participants receive either the drug or a placebo for 15 weeks. The study looks at safety, how the drug works in the body, and whether it can delay the need for standard immunoglobulin therapy.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Claseprubart (also called DNTH103)
What this could lead to
If it works, this could point toward a new treatment option for multifocal motor neuropathy that reduces the need for immunoglobulin therapy.
What could go wrong
This is an early Phase 2 trial with only 36 participants, so results may not apply to everyone. The drug may not prove effective or could have side effects.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for MULTIFOCAL MOTOR NEUROPATHY are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Cinical Study Site
RECRUITINGToronto, Canada
-
Cinical Study Site
RECRUITINGBeijing, 100053, China
-
Cinical Study Site
RECRUITINGShanghai, 200031, China
-
Cinical Study Site
RECRUITINGKuala Lumpur, 50586, Malaysia
-
Cinical Study Site
RECRUITINGKuala Lumpur, 59100, Malaysia
-
Cinical Study Site
RECRUITINGPermatang Pauh, 13700, Malaysia
-
Cinical Study Site
RECRUITINGSarawak, 93586, Malaysia
-
Cinical Study Site
RECRUITINGDaegu, South Korea
-
Cinical Study Site
RECRUITINGAlicante, 03010, Spain
-
Cinical Study Site
RECRUITINGBarcelona, 08041, Spain
-
Cinical Study Site
RECRUITINGIstanbul, 34093, Turkey (Türkiye)
-
Cinical Study Site #2
RECRUITINGSeoul, South Korea
-
Clinical Study Site
RECRUITINGScottsdale, Arizona, 85251, United States
-
Clinical Study Site
RECRUITINGLos Angeles, California, 90048, United States
-
Clinical Study Site
RECRUITINGBradenton, Florida, 34205, United States
-
Clinical Study Site
RECRUITINGTampa, Florida, 33620, United States
-
Clinical Study Site
RECRUITINGHonolulu, Hawaii, 96817, United States
-
Clinical Study Site
RECRUITINGKansas City, Kansas, 66103, United States
-
Clinical Study Site
RECRUITINGCincinnati, Ohio, 45219, United States
-
Clinical Study Site
RECRUITINGColumbus, Ohio, 43210, United States
-
Clinical Study Site
RECRUITINGHouston, Texas, 77030, United States
-
Clinical Study Site
RECRUITINGBeijing, 100730, China
-
Clinical Study Site
RECRUITINGAarhus, 8200, Denmark
-
Clinical Study Site
RECRUITINGCopenhagen, 1172, Denmark
-
Clinical Study Site
RECRUITINGMarseille, 13005, France
-
Clinical Study Site
RECRUITINGParis, 94000, France
-
Clinical Study Site
RECRUITINGRome, 00189, Italy
-
Clinical Study Site
RECRUITINGKota Kinabalu, 88200, Malaysia
-
Clinical Study Site
RECRUITINGAmsterdam, 1105, Netherlands
-
Clinical Study Site
RECRUITINGUtrecht, Netherlands
-
Clinical Study Site
RECRUITINGSkopje, North Macedonia
-
Clinical Study Site
RECRUITINGBydgoszcz, 85-090, Poland
-
Clinical Study Site
RECRUITINGKatowice, 40-689, Poland
-
Clinical Study Site
RECRUITINGKrakow, 30-688, Poland
-
Clinical Study Site
RECRUITINGKrakow, 31-202, Poland
-
Clinical Study Site
RECRUITINGBelgrade, 11000, Serbia
-
Clinical Study Site
RECRUITINGSeoul, South Korea
-
Clinical Study Site
RECRUITINGBarcelona, 08035, Spain
-
Clinical Study Site
RECRUITINGLondon, England, United Kingdom
-
Clinical Study Site
RECRUITINGOxford, England, United Kingdom
-
Clinical Study Site
RECRUITINGSalford, England, United Kingdom