Morton neuroma
MONDO:0700058Compressive neuropathy of the forefoot interdigital nerve chiefly due to compression and irritation at the plantar aspect of the transverse intermetatarsal ligament. It is not a true neuroma as the condition is degenerative rather than neoplastic. The most common location for Morton neuroma is between the 2nd and 3rd metatarsals.
Also known as: Morton entrapment, Morton metatarsalgia, interdigital nerve compression syndrome, interdigital neuralgia, interdigital neuritis, interdigital neuroma, intermetatarsal neuroma
6 clinical trials for this condition and its sub-types.
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New foot block may get you walking faster after surgery
Symptom relief CompletedThis study tested a new way to numb only the front part of the foot for surgery, leaving the heel sensation intact. The goal was to see if this approach could provide good pain relief while allowing patients to walk earlier. Twenty-seven adults having foot surgery received a targ…
Phase: NA • Sponsor: CMC Ambroise Paré • Aim: Symptom relief
Last updated Jun 27, 2026 13:06 UTC
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New Non-Opioid shot shows promise for stubborn foot nerve pain
Symptom relief CompletedThis early-phase study tested a single injection of resiniferatoxin (RTX), a non-opioid drug, in 3 adults with Morton's neuroma whose pain did not improve with standard treatments. The goal was to check safety and see if the injection could ease burning or shooting foot pain. Par…
Phase: PHASE1 • Sponsor: National Institutes of Health Clinical Center (CC) • Aim: Symptom relief
Last updated Jun 27, 2026 12:06 UTC
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Morton toe linked to faster muscles and better jumps in female footballers
Knowledge-focused CompletedThis study examined 47 female football players to see if those with Morton toe (a longer second toe) have different muscle and jumping abilities compared to those with normal feet. Researchers measured muscle contraction speed and reactive strength during jumps. The goal was to u…
Sponsor: Giresun University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC