New Non-Opioid shot shows promise for stubborn foot nerve pain

NCT ID NCT05695339

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase study tested a single injection of resiniferatoxin (RTX), a non-opioid drug, in 3 adults with Morton's neuroma whose pain did not improve with standard treatments. The goal was to check safety and see if the injection could ease burning or shooting foot pain. Participants were monitored for 4 weeks after the shot.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States