Mitral valve insufficiency
MONDO:1030008A mitral valve disorder characterized by incomplete valve closure.
Also known as: insufficiency, mitral, mitral insufficiency, mitral valve incompetence, mitral valve insufficiency/ regurgitation, congenital insufficiency of mitral valve, congenital mitral insufficiency, congenital mitral regurgitation
185 clinical trials for this condition and its sub-types.
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Broader categories
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Experimental heart valve device tested in just one patient — study halted
Disease control TerminatedThis early study tested a new device called the Cardiovalve Transfemoral Mitral Valve System in just one person with severe mitral regurgitation who was too high-risk for surgery. The device is inserted through a vein in the leg to replace the faulty mitral valve without open-hea…
Phase: NA • Sponsor: Cardiovalve Ltd. • Aim: Disease control
Last updated Jun 27, 2026 14:01 UTC
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Heart valve repair may unlock better drug dosing for heart failure
Knowledge-focused TerminatedThis registry tracks people with severe functional mitral regurgitation and heart failure who undergo a minimally invasive mitral valve repair called M-TEER. The goal is to see whether the repair allows patients to tolerate higher, guideline-recommended doses of heart failure med…
Sponsor: Institut für Pharmakologie und Präventive Medizin • Aim: Knowledge-focused
Last updated Aug 01, 2026 00:00 UTC