Microvillus inclusion disease
MONDO:0009635Microvillus inclusion disease (MVID) is a very rare, severe, malabsorbative syndrome characterized clinically by protracted or intractable neonatal secretory diarrhea and histologically by inclusion bodies on the intestinal epithelium.
Also known as: Davidson disease, MVID, MYO5B secretory diarrhea, MYO5B secretory diarrhoea, congenital familial protracted diarrhea with enterocyte brush-border abnormalities, congenital familial protracted diarrhoea with enterocyte brush-border abnormalities, congenital microvillous atrophy, congenital microvillus atrophy
9 clinical trials for this condition and its sub-types.
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New hope for kids with MVID: drug aims to cut diarrhea and IV needs
Disease control OngoingThis study tests a drug called crofelemer in 6 children with microvillus inclusion disease (MVID), a rare condition causing severe diarrhea and dependence on IV fluids. The drug is given as a powder mixed with water, three times a day, and compared to a placebo. The goal is to se…
Phase: PHASE2, PHASE3 • Sponsor: Napo Pharmaceuticals, Inc. • Aim: Disease control
Last updated Jun 27, 2026 13:05 UTC
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Massive data dive aims to improve GI care
Knowledge-focused ENROLLING_BY_INVITATIONThis study is a registry that will review medical records of 1,000 patients treated for benign or malignant gastrointestinal diseases between 2005 and 2030. Researchers will look at survival, symptoms like heartburn and swallowing trouble, and quality of life. The goal is to lear…
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC