New hope for kids with MVID: drug aims to cut diarrhea and IV needs
NCT ID NCT06721871
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a drug called crofelemer in 6 children with microvillus inclusion disease (MVID), a rare condition causing severe diarrhea and dependence on IV fluids. The drug is given as a powder mixed with water, three times a day, and compared to a placebo. The goal is to see if it safely reduces diarrhea and the need for IV support.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
crofelemer
What this could lead to
If it works, crofelemer could reduce the severe diarrhea and need for IV fluids in children with MVID, improving their daily life.
What could go wrong
This is a very small early-stage trial (6 children), so results may not apply to all patients. The drug may not work better than placebo, and side effects are possible.
Disclaimer
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the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Al Jalila Children's Hospital
Dubai, United Arab Emirates
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Boston Children's Hospital
Boston, Massachusetts, 02115, United States
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UOS Gastroenterolgia e Riabilitazione nutrizionale Piazza Sant' Onofrio 4
Rome, Italy