Mesothelioma
MONDO:0005065A usually malignant and aggressive neoplasm of the mesothelium which is often associated with exposure to asbestos.
Also known as: mesothelioma
1587 clinical trials for this condition and its sub-types, 94 tagged with Mesothelioma itself.
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Sub-types of Mesothelioma
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Malignant mesothelioma 37 trials · 108 incl. sub-types
11 sub-types
- Malignant pleural mesothelioma 71 trials · 75 incl. sub-types Sub-types →
- Malignant peritoneal mesothelioma 13 trials
- Malignant epithelioid mesothelioma 5 trials · 12 incl. sub-types Sub-types →
- Malignant biphasic mesothelioma 2 trials · 5 incl. sub-types Sub-types →
- Diffused pleural mesothelioma 3 trials
- Sarcomatoid mesothelioma 2 trials · 3 incl. sub-types Sub-types →
- Localized pleural mesothelioma 2 trials
- Malignant pericardial mesothelioma 0 trials
- Mesothelioma of the tunica vaginalis 0 trials
- Ovarian malignant mesothelioma 0 trials
- Pleural mesothelioma in situ 0 trials
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Pleural mesothelioma 28 trials · 86 incl. sub-types
2 sub-types
- Malignant pleural mesothelioma 71 trials · 75 incl. sub-types Sub-types →
- Pleural adenomatoid tumor 0 trials
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Peritoneal mesothelioma 14 trials · 22 incl. sub-types
5 sub-types
- Malignant peritoneal mesothelioma 13 trials
- Benign peritoneal mesothelioma 0 trials
- Peritoneal mesothelioma in situ 0 trials
- Peritoneal multicystic mesothelioma 0 trials
- Peritoneal well differentiated papillary mesothelioma 0 trials
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Adenomatoid tumor 0 trials
5 sub-types
- Adenomatoid tumour of the peritoneum 0 trials
- Epididymal adenomatoid tumor 0 trials
- Fallopian tube adenomatoid tumor 0 trials
- Pleural adenomatoid tumor 0 trials
- Uterine corpus adenomatoid tumor 0 trials
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Benign mesothelioma 0 trials
5 sub-types
- Benign peritoneal mesothelioma 0 trials
- Epididymal adenomatoid tumor 0 trials
- Fallopian tube adenomatoid tumor 0 trials
- Pleural adenomatoid tumor 0 trials
- Uterine corpus adenomatoid tumor 0 trials
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1 sub-type
Most studied deeper sub-types
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Oral drug VT3989 takes on chemo in mesothelioma survival test
Disease control Not yet recruitingResearchers are comparing an experimental oral drug called VT3989 with standard chemotherapy drugs gemcitabine or vinorelbine in adults with advanced epithelioid pleural mesothelioma. All participants have already received platinum-based chemotherapy and immunotherapy, and their …
Phase 3 • Sponsor: Vivace Therapeutics, Inc • Aim: Disease control
Last updated Sep 19, 2026 00:00 UTC
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New drug targets genetic weakness in mesothelioma tumors
Disease control Not yet recruitingThis phase 2 trial tests a drug called BMS-986504 in 30 people with relapsed mesothelioma whose tumors have a specific genetic marker (MTAP deficiency). The drug aims to shrink tumors by blocking a protein cancer cells need to grow. Researchers will measure how many patients have…
Phase 2 • Sponsor: University of Southampton • Aim: Disease control
Last updated Jun 27, 2026 12:36 UTC
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New immune cocktail takes on deadly mesothelioma
Disease control Not yet recruitingThis phase 2 trial tests whether adding two immune-boosting drugs (iparomlimab and tovorilimab) to standard chemotherapy and bevacizumab can shrink tumors in people with advanced mesothelioma who have not had prior treatment. About 37 participants will receive the combination eve…
Phase 2 • Sponsor: Fudan University • Aim: Disease control
Last updated Jun 27, 2026 12:04 UTC
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Experimental cell therapy targets Hard-to-Treat cancers
Disease control Not yet recruitingThis early-phase study tests a new cell therapy called KT032 in 24 adults with advanced solid tumors (ovarian, mesothelioma, colon cancer) that have spread to the abdomen and haven't responded to standard treatments. The main goal is to check safety and find the best dose, while …
Early phase 1 • Sponsor: Weijia Fang, MD • Aim: Disease control
Last updated Jun 27, 2026 09:05 UTC
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New imaging tracer could spot hidden cancers and fibrosis in one scan
Diagnosis Not yet recruitingThis study tests a new imaging tracer called [18F]FAPI-74, which attaches to a protein found on cells in tumors and scarred or inflamed tissue. Researchers want to see if it can show these areas more clearly than current scans. About 770 adults with various cancers or non-cancer …
Phase 1/2 • Sponsor: Martin Huellner • Aim: Diagnosis
Last updated Jul 17, 2026 00:00 UTC
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New breathing program aims to ease breathlessness in advanced lung cancer
Symptom relief Not yet recruitingThis study tests a short behavioral program called BREEZE+ to help people with advanced lung cancer manage breathlessness. The program includes three nurse-led sessions and a digital app that teaches breathing and relaxation skills. Researchers will compare this to usual care in …
Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated Jul 12, 2026 00:00 UTC