Maturity-onset diabetes of the young type 14
MONDO:0014674Any maturity-onset diabetes of the young in which the cause of the disease is a mutation in the APPL1 gene.
Also known as: APPL1 maturity-onset diabetes of the young (disease), MODY14, maturity-onset diabetes of the young (disease) caused by mutation in APPL1, maturity-onset diabetes of the young, type 14
64 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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New hope for kids: drug may prevent transplant complications
Disease control Not yet recruitingThis study tests whether adding the drug vorinostat to standard care can prevent graft-versus-host disease (GVHD) in children and young adults (ages 1-26) with non-cancerous blood disorders who are getting a bone marrow transplant. GVHD is a serious complication where donor cells…
Phase: PHASE2 • Sponsor: Sung Won Choi • Aim: Disease control
Last updated Jul 02, 2026 00:00 UTC
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12,000 diabetes patients to test remote monitoring system
Disease control Not yet recruitingThis study will look at whether a remote patient monitoring system, called Steno Detektor, helps people with diabetes control their blood sugar. About 12,000 patients will be monitored as part of their regular care. Researchers will compare blood sugar levels and hospital visits …
Sponsor: Steno Diabetes Center Copenhagen • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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AI could help spot rare metabolic diseases in newborns
Diagnosis Not yet recruitingThis trial will test an artificial intelligence system designed to interpret routine newborn screening tests for inherited metabolic disorders. Researchers will compare the AI's accuracy to standard manual review by trained staff. The study plans to include 200,000 newborns in Ch…
Phase: NA • Sponsor: The Children's Hospital of Zhejiang University School of Medicine • Aim: Diagnosis
Last updated Jun 27, 2026 09:00 UTC
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World's largest Real-World CGM study aims to unlock diabetes management secrets
Knowledge-focused Not yet recruitingThis global registry study follows 5,000 people with diabetes who use a Dexcom continuous glucose monitor (CGM). Researchers will track changes in HbA1c, a key measure of blood sugar control, over time. The goal is to understand how CGM use affects diabetes management in real-wor…
Sponsor: DexCom, Inc. • Aim: Knowledge-focused
Last updated Jul 04, 2026 00:00 UTC
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New app aims to bring Real-Time diabetes data to hospital dashboards
Knowledge-focused Not yet recruitingThis study tests a companion mobile app that wirelessly collects real-time glucose readings from Dexcom G7 continuous glucose monitors (CGMs) used by children with diabetes in the hospital. The app sends the data to a central hospital database, making it accessible to care teams …
Sponsor: Boston Children's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:03 UTC
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Tiny plastics found in human pancreas? new study investigates
Knowledge-focused Not yet recruitingThis study aims to detect and measure microplastics in pancreas tissue from 10 patients having pancreatic surgery. Researchers will also check fat tissue and blood samples. The goal is to see if microplastics are present and whether they might be linked to metabolic problems or c…
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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AI learns to read scans and reports for smarter disease diagnosis
Knowledge-focused Not yet recruitingThis study aims to create an artificial intelligence (AI) system that can combine medical images (like CT and MRI scans) with patient records and lab results to help doctors more accurately diagnose diseases of the liver, gallbladder, and pancreas. The researchers will use data f…
Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
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Diabetes and thyroid link: new study to check antibody levels
Knowledge-focused Not yet recruitingThis study will measure levels of a thyroid antibody called anti-thyroglobulin in 112 adults with diabetes. The goal is to see how common these antibodies are in diabetic patients, since diabetes and autoimmune thyroid disease often occur together. Participants will provide a blo…
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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Massive diabetes registry aims to unlock secrets of metabolic disease
Knowledge-focused Not yet recruitingThis 10-year observational study will follow 10,000 adults with diabetes, metabolic disorders, and related conditions like high blood pressure and fatty liver disease. Researchers will collect routine medical data to identify markers of disease severity and activity. The goal is …
Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
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New study to track hidden salt and mineral imbalances in sick kids
Knowledge-focused Not yet recruitingThis study will look at 150 infants and children aged 1 month to 4 years who are admitted to a hospital gastroenterology unit with a gastrointestinal disease. The goal is to find out how common electrolyte disturbances (like low sodium or potassium) are in these children. By meas…
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Jun 26, 2026 12:41 UTC