Male infertility with teratozoospermia due to single gene mutation
MONDO:0018394A rare, genetic male infertility due to sperm disorder characterized by the presence of spermatozoa with abnormal morphology, such as macrozoospermia or globozoospermia, in over 85% of sperm, resulting from mutation in a single gene known to cause teratozoospermia. It is a heterogeneous group that includes a wide range of abnormal sperm phenotypes affecting, solely or simultaneously, head, neck, midpiece, and/or tail.
4 clinical trials for this condition and its sub-types.
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Scientists probe gene behind male infertility and cystic fibrosis
Knowledge-focused Recruiting nowThis observational study aims to understand how the CFTR gene is regulated in epididymal cells, which may help explain male infertility linked to cystic fibrosis. Researchers will collect leftover tissue samples from 20 men already scheduled for surgery. No extra procedures are n…
Sponsor: University Hospital, Brest • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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New sperm-boosting method tested in 300 men
Knowledge-focused Recruiting nowThis study tests a new lab technique called HyperSperm to see if it can make sperm move better and stay healthy. Researchers will collect semen samples from 300 men with different fertility issues and compare the new method to the standard one. The goal is to find a safer and mor…
Sponsor: Fecundis Lab SL • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC