Long QT syndrome 3
MONDO:0011377An autosomal dominant condition caused by mutation(s) in the SCN5A gene, encoding sodium channel protein type 5 subunit alpha. It is characterized by a prolonged QT interval that may result in torsade de pointes, ventricular fibrillation and/or sudden cardiac death.
Also known as: LQT3, SCN5A long QT syndrome, long QT syndrome 3, long QT syndrome caused by mutation in SCN5A, long QT syndrome type 3, long QT syndrome 2/3, digenic, long QT syndrome 3, acquired, susceptibility to, long QT syndrome 3/6, digenic
33 clinical trials for this condition and its sub-types.
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New heart lead under watch: 5-Year safety check begins
Disease control ENROLLING_BY_INVITATIONThis study follows 2000 people who have or will get the OmniaSecure defibrillation lead, a wire that helps control dangerous heart rhythms. Researchers will track how often the lead causes problems over 5 years. The goal is to make sure the lead is safe and works as expected in e…
Sponsor: Medtronic • Aim: Disease control
Last updated Aug 05, 2026 00:00 UTC
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New antibiotic pouch aims to stop infections in heart device patients
Disease control OngoingThis study is tracking 100 adults who receive an EluPro antibiotic-eluting envelope during implantation of a heart device (like a pacemaker). The envelope slowly releases antibiotics to prevent infection. Researchers are monitoring complication rates in real-world use to see how …
Sponsor: Elutia Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:39 UTC
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Heart device DiamondTemp under Real-World watch: will it deliver?
Knowledge-focused OngoingThis registry follows 545 people with arrhythmia who received a heart ablation using the DiamondTemp system. Researchers will track how many stay free of their heart rhythm problem and how many have serious side effects over 12 months. The goal is to see how well the device works…
Sponsor: Medtronic Cardiac Ablation Solutions • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:37 UTC
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Watching embryos grow: a new way to pick the best for IVF?
Knowledge-focused ENROLLING_BY_INVITATIONThis study watches embryos grow using time-lapse cameras and compares their development to genetic test results. Researchers hope to find visual clues that indicate a healthy embryo. 2000 IVF patients are taking part. If a link is found, it could lead to a less invasive way to ch…
Sponsor: Gattaca Genomics • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC