Lipedema
MONDO:0013577Disorder of adipose tissue characterized by symmetric and bilateral enlargement of the lower extremities due to abnormal deposition of subcutaneous fat often in obese women. It is associated with hematoma, pain and may progress to secondary lymphedema which is known as lipolymphedema.
Also known as: Lipedema (disease), lipedema
28 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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New imaging technique could shed light on lymphatic disorders
Diagnosis ENROLLING_BY_INVITATIONThis study uses a special camera and a safe dye to take pictures of the lymphatic system, which helps move fluid in the body. Researchers want to see how this system works in healthy people and in those with conditions like lymphedema or lipedema. The goal is to find patterns tha…
Sponsor: The University of Texas Health Science Center, Houston • Aim: Diagnosis
Last updated Jun 27, 2026 11:00 UTC
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New injection aims to soothe painful fat lumps
Symptom relief OngoingThis phase 2 trial tests whether CBL-514 injections can reduce pain from lipomas in people with Dercum's disease. Nineteen adults with at least 4 painful lipomas will receive either the drug or a placebo. The main goal is to see if the treatment lowers pain scores.
Phase: PHASE2 • Sponsor: Caliway Biopharmaceuticals Co., Ltd. • Aim: Symptom relief
Last updated Jun 27, 2026 12:07 UTC
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Exercise as medicine: HIIT may soothe lipedema pain
Symptom relief OngoingThis study tests whether 12 weeks of high-intensity interval training (HIIT) can reduce pain and improve quality of life in 62 women with lipedema, a chronic fat disorder causing painful leg swelling. Participants will do HIIT three times a week and then switch to usual care, or …
Phase: NA • Sponsor: Norwegian University of Science and Technology • Aim: Symptom relief
Last updated Jun 27, 2026 08:02 UTC
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Can liposuction ease the pain of lipedema? major norwegian trial aims to find out
Symptom relief OngoingThis national study in Norway is testing whether liposuction can reduce pain and improve quality of life for women with lipedema, a chronic condition causing painful fat buildup in the limbs. Researchers will compare early versus delayed liposuction, along with standard treatment…
Phase: NA • Sponsor: Haraldsplass Deaconess Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 07:51 UTC