New injection aims to soothe painful fat lumps

NCT ID NCT06303570

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 2 trial tests whether CBL-514 injections can reduce pain from lipomas in people with Dercum's disease. Nineteen adults with at least 4 painful lipomas will receive either the drug or a placebo. The main goal is to see if the treatment lowers pain scores.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
CBL-514 injection
What this could lead to
If it works, this could point toward a non-surgical treatment to ease pain from Dercum's disease lipomas.
What could go wrong
This is a very small, early phase 2 study with only 19 people. The results may not apply to everyone, and the treatment might not work better than placebo.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for DERCUM'S DISEASE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Investigator Site

    Spokane, Washington, 99204, United States