Laryngotracheoesophageal cleft
MONDO:0016060A laryngo-tracheo-esophageal cleft (LC) is a congenital malformation characterized by an abnormal, posterior, sagittal communication between the larynx and the pharynx, possibly extending downward between the trachea and the esophagus.
Also known as: LC, LTEC, Larnygeotracheoesophageal cleft, congenital cleft larynx, laryngeal cleft, laryngo-tracheo-esophageal cleft, laryngo-tracheo-esophageal diastema, tracheal cleft
16 clinical trials for this condition and its sub-types.
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Broader categories
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Gel or stitches? new study aims to help kids swallow safely
Symptom relief ENROLLING_BY_INVITATIONThis study looks at two different procedures to help children aged 1 to 10 years who have trouble swallowing due to a laryngeal cleft (a gap in the airway). One procedure injects a gel to build up the airway wall, the other uses stitches to close the gap. The goal is to see which…
Phase: NA • Sponsor: Oregon Health and Science University • Aim: Symptom relief
Last updated Jun 27, 2026 07:52 UTC
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Massive data dive aims to improve GI care
Knowledge-focused ENROLLING_BY_INVITATIONThis study is a registry that will review medical records of 1,000 patients treated for benign or malignant gastrointestinal diseases between 2005 and 2030. Researchers will look at survival, symptoms like heartburn and swallowing trouble, and quality of life. The goal is to lear…
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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New breath test could replace painful lung scopes
Knowledge-focused ENROLLING_BY_INVITATIONThis study aims to see if a simple, non-invasive breathing test can accurately measure the acidity (pH) in the airways, which is often abnormal in lung diseases. Researchers will compare results from this breath test with standard methods in 150 healthy volunteers and people with…
Phase: PHASE2 • Sponsor: Indiana University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC