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Lactic acidosis

MONDO:0006040

Metabolic acidosis characterized by the accumulation of lactate in the body. It is caused by tissue hypoxia.

8 clinical trials for this condition and its sub-types.

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Sub-types

Acquired lactic acidosis (0) Cardiomyopathy-hypotonia-lactic acidosis syndrome (0) Mitochondrial DNA depletion syndrome 9 (0)

Broader categories

Disease (680) Metabolic disease (233) Human disease (14) Disease by developmental or physiological process (0)

Trials to join now! 3 Not yet recruiting 1 Not yet finished but already full! 1 Completed 3

New hope for MELAS: experimental drug tested for Long-Term safety

Disease control Ongoing

This study is testing the long-term safety of a daily oral drug called zagociguat in 44 adults with MELAS, a rare genetic disease that affects energy production in cells. All participants previously completed a lead-in study of the same drug. Researchers will monitor side effects…

Phase: PHASE2 • Sponsor: Tisento Therapeutics • Aim: Disease control

Last updated Jul 09, 2026 00:00 UTC