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Lactic acidosis

MONDO:0006040

Metabolic acidosis characterized by the accumulation of lactate in the body. It is caused by tissue hypoxia.

8 clinical trials for this condition and its sub-types.

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Sub-types

Acquired lactic acidosis (0) Cardiomyopathy-hypotonia-lactic acidosis syndrome (0) Mitochondrial DNA depletion syndrome 9 (0)

Broader categories

Disease (680) Metabolic disease (233) Human disease (14) Disease by developmental or physiological process (0)

Trials to join now! 3 Not yet recruiting 1 Not yet finished but already full! 1 Completed 3

Experimental drug aims to boost energy in rare genetic disorders

Disease control Not yet recruiting

This study tests an oral drug called glycerol tributyrate in 24 adults with MELAS or LHON-Plus, two rare mitochondrial diseases that cause severe symptoms like strokes and vision loss. The trial is open-label (everyone gets the drug) and uses each person as their own control over…

Phase: PHASE1, PHASE2 • Sponsor: George Washington University • Aim: Disease control

Last updated Jun 27, 2026 13:02 UTC