Keratinopathic ichthyosis

This early-phase trial tests whether low doses of erlotinib, a drug originally used for cancer, can improve symptoms of rare genetic skin conditions called keratinopathies. About 44 adults with confirmed diagnoses will take increasing doses over 24 weeks. The goal is to see if it…

This study tests whether Changji'an capsules, a traditional Chinese medicine, can reduce diarrhea and stomach pain in people with irritable bowel syndrome (IBS) where diarrhea is the main symptom. About 636 adults aged 18 to 65 will take the capsule or a placebo for 8 weeks. The …

This study tests whether a small, watch-sized device that delivers mild electrical stimulation to the skin can improve symptoms in people with diarrhea-predominant irritable bowel syndrome (IBS-D). Researchers will compare the real device to a sham (fake) version in 200 adults ag…

This study looks at how people with skin conditions (like eczema, psoriasis, or skin cancer) manage stress, feel lonely, and bounce back from challenges. Researchers will compare 375 adults with and without skin disease across 15 European countries using questionnaires. The goal …

This study will create and test simple picture-based tools (pictograms) to help children aged 8 to 17 describe symptoms like constipation, bloating, and stomach pain. Many kids struggle to explain what they feel, which can lead to misdiagnosis. The goal is to see if these pictogr…