Isolated tracheo-esophageal fistula
MONDO:0018694A rare, congenital, esophageal disorder characterized by the presence of an abnormal connection between the esophagus and the trachea (typically occurring in the lower cervical or upper thoracic area and taking an oblique path upward to trachea), without concomitant esophageal atresia. Depending on the size of the lumen, presentation varies from neonatal episodes of choking and cyanosis on feeding to subtle symptoms of wheezing and recurrent respiratory infections in childhood or early adulthood.
Also known as: H-type tracheoesophageal fistula, tracheo-esophageal fistula, tracheoesophageal fistula, isolated tracheoesophageal fistula
8 clinical trials for this condition and its sub-types.
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New study reviews best ways to patch holes in the esophagus
Disease control CompletedThis study looked at how well endoscopic stenting and suturing work to close holes or tears in the esophagus. Researchers reviewed 150 patients treated at a large referral center. The goal was to see which technique leads to better healing.
Sponsor: Indiana University • Aim: Disease control
Last updated Jun 27, 2026 09:06 UTC
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New hope for preventing Post-Surgery confusion in seniors
Symptom relief CompletedThis study tested whether giving a small amount of s-ketamine during chest surgery could reduce the risk of postoperative delirium (sudden confusion) in patients aged 60 and older. Over 500 participants were randomly assigned to receive either s-ketamine or another drug (dexmedet…
Phase: EARLY_PHASE1 • Sponsor: Affiliated Cancer Hospital & Institute of Guangzhou Medical University • Aim: Symptom relief
Last updated Jun 27, 2026 12:28 UTC