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Isolated adrenal insufficiency

MONDO:0100315

An ABCD1 deficiency that presents with primary adrenocortical insufficiency between age two years and adulthood and most commonly by age 7.5 years, without evidence of neurologic abnormality; however, some degree of neurologic disability (most commonly adrenomyeloneuropathy (AMN)) usually develops by middle age.

Also known as: isolated adrenal insufficiency

3 clinical trials for this condition and its sub-types.

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Dementia (698) Disease (680) Psychiatric disorder (435) Cognitive disorder (433) Metabolic disease (233) Nervous system disorder (231) Hereditary disease (176) Neurodegenerative disease (171) Central nervous system disorder (107) Endocrine system disorder (72)
Trials to join now! 1 Not yet recruiting 1 Completed 1
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  • New imaging tracer could shed light on adrenal cholesterol

    Knowledge-focused Recruiting now

    This study tests a special radioactive tracer called [18F]FNP-59 to see if it can safely and clearly show cholesterol activity in the adrenal gland using PET scans. About 24 people will take part, including healthy volunteers and those with known adrenal problems. The goal is to …

    Phase: EARLY_PHASE1 • Sponsor: Benjamin Viglianti • Aim: Knowledge-focused

    Last updated Jun 27, 2026 08:02 UTC

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