Intrahepatic cholestasis
MONDO:0019072A cholestasis characterized by impairment of the bile flow caused by obstruction located in the liver.
35 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsSub-types
Broader categories
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One shot during c-section may stop unbearable itching for moms with liver condition
Symptom relief Not yet recruitingThis study tests whether giving a single intravenous dose of esketamine during a C-section can reduce the intense itching that often follows surgery in women with intrahepatic cholestasis of pregnancy. 160 women will be randomly assigned to receive either esketamine or a placebo …
Phase: NA • Sponsor: Tianjin Medical University General Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:28 UTC
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New hope for Moms-to-Be: drug targets dangerous pregnancy itch
Symptom relief Not yet recruitingThis early-stage study tests a drug called maralixibat in 28 pregnant women with intrahepatic cholestasis of pregnancy (ICP), a liver condition that causes severe itching and high bile acids. The main goal is to see if the drug is safe and tolerable for both mother and baby. Rese…
Phase: PHASE2 • Sponsor: Imperial College London • Aim: Symptom relief
Last updated Jun 27, 2026 09:02 UTC
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1,000 patients to help unlock secrets of liver surgery recovery
Knowledge-focused Not yet recruitingThis study will follow 1,000 adults who have liver or bile duct surgery at one hospital in Italy. Researchers will track complications, survival, and cancer recurrence for up to 5 years. The goal is to better understand what affects recovery and long-term health after these opera…
Sponsor: Azienda USL Toscana Centro • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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New study to track hidden salt and mineral imbalances in sick kids
Knowledge-focused Not yet recruitingThis study will look at 150 infants and children aged 1 month to 4 years who are admitted to a hospital gastroenterology unit with a gastrointestinal disease. The goal is to find out how common electrolyte disturbances (like low sodium or potassium) are in these children. By meas…
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Jun 26, 2026 12:41 UTC