Intrahepatic cholestasis
MONDO:0019072A cholestasis characterized by impairment of the bile flow caused by obstruction located in the liver.
29 clinical trials for this condition and its sub-types.
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One shot during c-section may stop unbearable itching for moms with liver condition
Symptom relief Not yet recruitingThis study tests whether giving a single intravenous dose of esketamine during a C-section can reduce the intense itching that often follows surgery in women with intrahepatic cholestasis of pregnancy. 160 women will be randomly assigned to receive either esketamine or a placebo …
Phase: NA • Sponsor: Tianjin Medical University General Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:28 UTC
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New hope for Moms-to-Be: drug targets dangerous pregnancy itch
Symptom relief Not yet recruitingThis early-stage study tests a drug called maralixibat in 28 pregnant women with intrahepatic cholestasis of pregnancy (ICP), a liver condition that causes severe itching and high bile acids. The main goal is to see if the drug is safe and tolerable for both mother and baby. Rese…
Phase: PHASE2 • Sponsor: Imperial College London • Aim: Symptom relief
Last updated Jun 27, 2026 09:02 UTC