Intraepithelial neoplasia

This trial compares two surgical methods for removing oral epithelial dysplasia, a precancerous condition of the mouth lining. One group receives laser surgery, while the other has traditional scalpel removal. Researchers measure wound healing speed, swelling, redness, and pain t…

This study tested the drug pembrolizumab (Keytruda) in 15 people with high-risk precancerous mouth lesions. The goal was to see if the drug could prevent these lesions from turning into oral cancer. Participants were randomly assigned to receive the drug or just be watched. The s…

This study tested a procedure called radiofrequency ablation (using heat to remove abnormal cells) in 125 people with Barrett's esophagus and low-grade dysplasia. Participants were randomly assigned to receive the ablation or regular endoscopic monitoring. The goal was to see if …

This study tested a non-invasive optical device that uses different types of light to detect and diagnose various mouth conditions, including oral cancer, gum disease, and dry mouth. Over 1,000 participants with and without oral lesions were imaged, and the results were compared …

This study tested whether a gel called PuraBond, applied to the surgical wound during mouth or throat surgery, can reduce pain and bleeding afterward. 73 patients were randomly assigned to receive the gel or not. Researchers measured pain levels over 30 days and tracked complicat…

This completed study looked back at medical records of 500 patients aged 50 or younger diagnosed with colorectal cancer or precancerous growths at a hospital in Shenzhen, China. Researchers compared those with early-stage disease to those with later-stage disease to identify fact…