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Internal carotid artery stenosis

MONDO:0005189

Carotid stenosis is a narrowing or constriction of the inner surface (lumen) of the carotid artery, usually caused by atherosclerosis. The internal carotid artery supplies the brain. Plaque often builds up at that division, and causes a narrowing (stenosis). Pieces of plaque can break off and block the small arteries above in the brain, which causes a stroke. Plaque can also build up at the origin of the carotid artery at the aorta.

15 clinical trials for this condition and its sub-types.

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Broader categories

Cardiovascular disorder (1093) Disease (717) Nervous system disorder (243) Vascular disorder (138) Brain disorder (131) Central nervous system disorder (115) Cerebrovascular disorder (104) Human disease (15) Neurovascular disorder (5) Disease by body system or component (0)
Trials to join now! 7 Not yet recruiting 6 Not yet finished but already full! 1 Completed 1
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  • Brain blood flow fix may reverse thinking decline

    Knowledge-focused Completed

    This study looks at people with severe but symptom-free narrowing of the carotid artery in the neck. It tests whether opening the artery with surgery or stenting can improve memory and thinking problems caused by poor blood flow to the brain. About 385 participants from a larger …

    Phase 3 • Sponsor: Columbia University • Aim: Knowledge-focused

    Last updated Aug 20, 2026 00:00 UTC

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