Idiopathic subglottic stenosis

This phase 2 trial tested the drug Taltz (ixekizumab) in 10 people with idiopathic subglottic stenosis, a rare condition where scar tissue narrows the airway. The goal was to see if blocking IL-17A could slow scar formation and lengthen the time between needed surgeries. Particip…

This early-phase trial tested whether the immunosuppressant drug everolimus could help people with idiopathic subglottic stenosis, a rare condition where scarring narrows the airway. Eight participants took everolimus for 42 days after a dilation surgery to open the airway. The g…

This study looked at whether giving a low dose of a muscle relaxant (rocuronium) during bronchoscopy—a procedure where a tube is inserted into the lungs—could reduce complications like throat spasms and coughing. 153 adults having elective bronchoscopy were split into two groups:…

This study looked at how using high-flow nasal oxygen during laryngeal surgery affects the heart and blood vessels. Twenty relatively healthy adults were monitored for changes in heart function compared to standard breathing support. The goal was to understand potential risks, no…

This completed study tested two ways of helping patients breathe during microscopic throat surgery. One method uses a steady airflow, while the other uses a set volume of air. The goal was to see which method keeps airway pressure lower and safer. 68 adults having elective laser …