Idiopathic malabsorption due to bile acid synthesis defects
MONDO:0019393Idiopathic malabsorption due to increased acid bile synthesis is an intestinal disease of unknown etiology characterized by an overproduction of bile acids which leads to chronic watery diarrhea.
Also known as: idiopathic bile acid malabsorption
6 clinical trials for this condition and its sub-types.
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Could a common cholesterol drug ease chronic diarrhoea?
Symptom relief OngoingThis study tests whether atorvastatin, a drug typically used for cholesterol, can reduce bile acid production and improve symptoms in people with bile acid diarrhoea (BAD). Twenty adults with moderate-to-severe BAD will receive atorvastatin and a placebo in random order, each for…
Phase: PHASE4 • Sponsor: Asger Lund, MD • Aim: Symptom relief
Last updated Aug 13, 2026 00:00 UTC
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Can a decade of real-world data refine treatment for rare bile acid disorders?
Knowledge-focused OngoingThis study is a patient registry that will follow people of any age with bile acid synthesis disorders who are treated with Cholbam (cholic acid). The goal is to collect information over 10 years on how the drug performs in routine clinical care, including its safety, effectivene…
Sponsor: Mirum Pharmaceuticals, Inc. • Aim: Knowledge-focused
Last updated Aug 02, 2026 00:00 UTC