Could a common cholesterol drug ease chronic diarrhoea?
NCT ID NCT07042165
First seen Jun 27, 2026 · Last updated Aug 12, 2026 · Updated 4 times
Summary
This study tests whether atorvastatin, a drug typically used for cholesterol, can reduce bile acid production and improve symptoms in people with bile acid diarrhoea (BAD). Twenty adults with moderate-to-severe BAD will receive atorvastatin and a placebo in random order, each for four weeks. The goal is to see if the drug lowers bile acid levels and reduces stool frequency and urgency.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- atorvastatin
- What this could lead to
- If it works, this could offer a new treatment option for bile acid diarrhoea, reducing symptoms like stomach pain and urgent bowel movements.
- What could go wrong
- This is a small, early proof-of-concept trial with only 20 participants. The results may not apply to everyone, and atorvastatin may not improve symptoms or could cause side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Center for Clinical Metabolic Research, Gentofte Hospital
Hellerup, 2900, Denmark
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