Could a common cholesterol drug ease chronic diarrhoea?

NCT ID NCT07042165

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether atorvastatin, a drug typically used for cholesterol, can reduce bile acid production and improve symptoms in people with bile acid diarrhoea (BAD). Twenty adults with moderate-to-severe BAD will receive atorvastatin and a placebo in random order, each for four weeks. The goal is to see if the drug lowers bile acid levels and reduces stool frequency and urgency.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

atorvastatin

What this could lead to

If it works, this could offer a new treatment option for bile acid diarrhoea, reducing symptoms like stomach pain and urgent bowel movements.

What could go wrong

This is a small, early proof-of-concept trial with only 20 participants. The results may not apply to everyone, and atorvastatin may not improve symptoms or could cause side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

bile acid malabsorption, primary, 1 idiopathic malabsorption due to bile acid synthesis defects

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Center for Clinical Metabolic Research, Gentofte Hospital

    RECRUITING

    Hellerup, 2900, Denmark

    Contact Phone: •••-•••-•••• Email: •••••@•••••