Hypogonadotropic hypogonadism
MONDO:0018555Abnormal ovarian or testicular function due to insufficient hormonal stimulation from the hypothalamic-pituitary axis.
Also known as: Normosmic idiopathic hypogonadotropic hypogonadism, central hypogonadism, gonadotropic deficiency, hypogonadism, hypogonadotropic, hypogonadotropic hypogonadism, hypogonadotropic hypogonadism with or without anosmia, low gonadotropins (secondary hypogonadism), nIHH
100 clinical trials for this condition and its sub-types, 19 tagged with Hypogonadotropic hypogonadism itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Hypogonadotropic hypogonadism
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Congenital hypogonadotropic hypogonadism 0 trials · 83 incl. sub-types
25 sub-types
- Combined pituitary hormone deficiencies, genetic form 1 trial · 42 incl. sub-types Sub-types →
- Prader-Willi syndrome 32 trials Sub-types →
- CHARGE syndrome 4 trials Sub-types →
- Hypogonadotropic hypogonadism 7 with or without anosmia 3 trials
- Arhinia, choanal atresia, and microphthalmia 1 trial
- Isolated congenital hypogonadotropic hypogonadism 0 trials · 1 incl. sub-types Sub-types →
- Obesity due to congenital leptin deficiency 1 trial
- Obesity due to leptin receptor gene deficiency 1 trial
- Obesity due to prohormone convertase I deficiency 1 trial
- ANE syndrome 0 trials
- Kallmann syndrome-heart disease syndrome 0 trials
- Laurence-Moon syndrome 0 trials
- Martsolf syndrome 1 0 trials
- Moebius syndrome-axonal neuropathy-hypogonadotropic hypogonadism syndrome 0 trials
- Prader-Willi-like syndrome 0 trials Sub-types →
- Woodhouse-Sakati syndrome 0 trials
- X-linked adrenal hypoplasia congenita 0 trials Sub-types →
- Ataxia-hypogonadism-choroidal dystrophy syndrome 0 trials
- Brachytelephalangy-dysmorphism-Kallmann syndrome 0 trials
- Cerebellar ataxia-hypogonadism syndrome 0 trials Sub-types →
- Familial adrenal hypoplasia with absent pituitary luteinizing hormone 0 trials
- Hypogonadotropic hypogonadism-frontoparietal alopecia syndrome 0 trials
- Hypogonadotropic hypogonadism-retinitis pigmentosa syndrome 0 trials
- Hypogonadotropic hypogonadism-severe microcephaly-sensorineural hearing loss-dysmorphism syndrome 0 trials
- Polyendocrine-polyneuropathy syndrome 0 trials
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Kallmann syndrome 3 trials
18 sub-types
- Hypogonadotropic hypogonadism 1 with or without anosmia 0 trials
- Hypogonadotropic hypogonadism 11 with or without anosmia 0 trials
- Hypogonadotropic hypogonadism 14 with or without anosmia 0 trials
- Hypogonadotropic hypogonadism 15 with or without anosmia 0 trials
- Hypogonadotropic hypogonadism 16 with or without anosmia 0 trials
- Hypogonadotropic hypogonadism 17 with or without anosmia 0 trials
- Hypogonadotropic hypogonadism 18 with or without anosmia 0 trials
- Hypogonadotropic hypogonadism 19 with or without anosmia 0 trials
- Hypogonadotropic hypogonadism 2 with or without anosmia 0 trials
- Hypogonadotropic hypogonadism 20 with or without anosmia 0 trials
- Hypogonadotropic hypogonadism 21 with or without anosmia 0 trials
- Hypogonadotropic hypogonadism 22 with or without anosmia 0 trials
- Hypogonadotropic hypogonadism 3 with or without anosmia 0 trials
- Hypogonadotropic hypogonadism 4 with or without anosmia 0 trials
- Hypogonadotropic hypogonadism 5 with or without anosmia 0 trials
- Hypogonadotropic hypogonadism 6 with or without anosmia 0 trials
- Hypogonadotropic hypogonadism 8 with or without anosmia 0 trials
- Hypogonadotropic hypogonadism 9 with or without anosmia 0 trials
Most studied deeper sub-types
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Can a simple muscle exercise improve erectile function in men with low testosterone?
Disease control Not yet recruitingThis study tests whether pelvic floor muscle training (PFMT) with a handheld biofeedback device can improve erectile function and sexual quality of life in men with functional hypogonadism (low testosterone) and erectile dysfunction. Participants are randomly assigned to PFMT wit…
Sponsor: Poznan University of Physical Education • Aim: Disease control
Last updated Jul 09, 2026 00:00 UTC
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Can a natural supplement boost testosterone and improve sex life in aging men?
Symptom relief Not yet recruitingThis study looks at whether a natural supplement called D-Chiro-inositol can help men aged 50 to 75 who have low testosterone (functional hypogonadism) and related sexual issues. Over 3 months, 35 men will take the supplement to see if their hormone levels and sexual function imp…
Sponsor: Cardarelli Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:33 UTC
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Testicle blood flow may predict fertility surgery success
Knowledge-focused Not yet recruitingThis study looks at 40 infertile men with varicoceles (enlarged veins in the scrotum) to see if blood flow measurements in the testicles can predict how well they will respond to surgery. Participants will have ultrasound and blood tests before and three months after a standard m…
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC