Hypercholesterolemia, familial, 1
MONDO:0007750Also known as: FHCL1, LDL cholesterol level QTL2, LDL receptor disorder, hypercholesterolemia, familial, hypercholesterolemia, familial, 1, hypercholesterolemia, familial, due to ldlr defect, modifier of, hypercholesterolemia, familial, modifier of, hypercholesterolemic xanthomatosis, familial
19 clinical trials for this condition and its sub-types.
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New pill could slash heart risks for millions
Disease control OngoingThis Phase 3 trial is testing an oral drug called MK-0616 (enlicitide decanoate) in about 14,550 people at high risk for heart problems. The drug aims to lower cholesterol and reduce the chance of major events like heart attacks, strokes, and emergency artery procedures. Particip…
Phase: PHASE3 • Sponsor: Merck Sharp & Dohme LLC • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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New study aims to boost statin use with simple doctor nudges
Disease control OngoingThis study tests two methods to increase referrals to a centralized pharmacy service for managing statin therapy in patients with or at high risk for heart disease. One method sends reminders to doctors during office visits, and the other sends electronic messages outside of visi…
Phase: NA • Sponsor: University of Pennsylvania • Aim: Disease control
Last updated Jun 27, 2026 12:04 UTC
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Leqvio safety under the microscope: Real-World data on 585 patients
Knowledge-focused OngoingThis study tracks 585 patients with familial or regular high cholesterol who are already prescribed Leqvio. Researchers will monitor side effects and cholesterol levels over time to see how safe and effective the drug is in everyday use. No new treatment is given—it's purely obse…
Sponsor: Novartis Pharmaceuticals • Aim: Knowledge-focused
Last updated Aug 08, 2026 00:03 UTC