Hypercholesterolemia, familial, 1
MONDO:0007750Also known as: FHCL1, LDL cholesterol level QTL2, LDL receptor disorder, hypercholesterolemia, familial, hypercholesterolemia, familial, 1, hypercholesterolemia, familial, due to ldlr defect, modifier of, hypercholesterolemia, familial, modifier of, hypercholesterolemic xanthomatosis, familial
19 clinical trials for this condition and its sub-types.
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Plant power: natural extract shows promise for high cholesterol
Disease control CompletedThis study tested whether a special extract from plants (phytosterols and phytostanols) can help lower cholesterol levels in adults with high cholesterol. 42 people took either the extract or a placebo for a period of time. The main goal was to see if the extract could reduce tot…
Phase: NA • Sponsor: Desirée Victoria Montesinos • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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Could a probiotic be the next Heart-Healthy superfood?
Disease control CompletedThis study tested whether a probiotic called Lactobacillus mucosae DPC6426 can lower cholesterol in healthy adults with mildly high levels. Over 12 weeks, 94 participants took either the probiotic or a placebo. The goal was to see if this natural approach could offer a heart-heal…
Phase: NA • Sponsor: University College Cork • Aim: Disease control
Last updated Jun 27, 2026 12:05 UTC
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New hope for high cholesterol: Statin-Free drug shows promise in Year-Long study
Disease control CompletedThis study tested a daily pill called ETC-1002 in 130 adults with very high LDL ("bad") cholesterol who either didn't respond well to statins or had side effects from them. Over 52 weeks, researchers checked how safe the drug was and how much it lowered cholesterol. The goal was …
Phase: PHASE3 • Sponsor: Otsuka Pharmaceutical Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 09:07 UTC
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Heart attack patients under 60 get genetic screening for hidden cholesterol disorder
Diagnosis CompletedThis study tested whether offering genetic screening to younger heart attack patients (under 60) can uncover hidden cases of Familial Hypercholesterolemia (FH), an inherited condition causing very high cholesterol. Researchers recruited 140 patients admitted with a heart attack a…
Phase: NA • Sponsor: University of British Columbia • Aim: Diagnosis
Last updated Jun 27, 2026 12:28 UTC
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Generic cholesterol drug shows promise in early comparison
Knowledge-focused CompletedThis completed study tested whether a generic bempedoic acid tablet works the same as the brand-name drug Nilemdo in 32 healthy adults. Participants took a single dose of each under fasting conditions, and researchers measured drug levels in the blood. The goal was to see if the …
Phase: PHASE1 • Sponsor: Humanis Saglık Anonim Sirketi • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:45 UTC