Hippocampal sclerosis of aging
MONDO:0005544Age-related neuropathological condition with severe neuronal cell loss and gliosis in the hippocampus
5 clinical trials for this condition and its sub-types.
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Could a heart pill slow a hidden dementia?
Disease control OngoingThis study tests whether nicorandil, a drug currently used for heart conditions, can help people with a type of dementia called hippocampal sclerosis of aging. This condition is often mistaken for Alzheimer's but has no approved treatments. The trial includes 64 older adults and …
Phase: PHASE2 • Sponsor: Gregory Jicha, MD, PhD • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC
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AI boosts brain scan accuracy in massive new trial
Diagnosis ENROLLING_BY_INVITATIONThis study tests whether an AI tool can help radiologists read brain CT and MRI scans more accurately and quickly. Researchers will compare how well doctors, AI alone, and doctors using AI together can spot abnormalities, urgent findings, and classify diseases. The goal is to red…
Sponsor: Yaou Liu • Aim: Diagnosis
Last updated Jun 27, 2026 11:00 UTC
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Scientists dig into brain genes to unlock epilepsy mysteries
Knowledge-focused OngoingThis study looks at gene activity in brain tissue removed during surgery from 10 people with temporal lobe epilepsy and hippocampal sclerosis. The goal is to find which genes are linked to the disease and may help predict outcomes. No new treatment is being tested; instead, resea…
Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:25 UTC
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300 volunteers help create medical image bank for science
Knowledge-focused OngoingThis study gathers MRI, CT, and ultrasound images from 300 adults—some healthy, some with kidney or brain disease—to build a collection for future not-for-profit research. No new treatments are being tested; the goal is to make medical images available to scientists for advancing…
Sponsor: Mario Negri Institute for Pharmacological Research • Aim: Knowledge-focused
Last updated Jun 26, 2026 13:28 UTC