Heritable pulmonary arterial hypertension
MONDO:0017148Heritable pulmonary arterial hypertension (HPAH) is a form of pulmonary arterial hypertension (PAH), occurring due to mutations in PAH predisposing genes or in a familial context. HPAH is characterized by elevated pulmonary arterial resistance leading to right heart failure. HPAH is progressive and potentially fatal.
Also known as: FPAH, HPAH, HpaH, familial pulmonary arterial hypertension, hereditary pulmonary arterial hypertension
34 clinical trials for this condition and its sub-types, 10 tagged with Heritable pulmonary arterial hypertension itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Heritable pulmonary arterial hypertension
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Pulmonary hypertension, primary, 1 0 trials
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Pulmonary hypertension, primary, 5 0 trials
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Pulmonary hypertension, primary, 6 0 trials
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Pulmonary hypertension, primary, 7 0 trials
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Fat in the heart: new clues for PAH?
Knowledge-focused Recruiting nowThis study examines why fat accumulates in the right ventricle of people with pulmonary arterial hypertension (PAH) and how it affects heart function and exercise ability. Researchers will use MRI and blood tests in 75 adults with PAH to track changes over time. The goal is to be…
Sponsor: Vanderbilt University Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Cash for Kids' brains: brazil study tests if $40 a month boosts mental health
Knowledge-focused Recruiting nowThis study looks at whether giving mothers in Brazil an extra $40 per month (compared to just $2) can protect their children's brain development and mental health. About 450 children aged 7-10 from low-income families will be followed for 2 years. Researchers will measure stress,…
Sponsor: New York State Psychiatric Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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New study seeks clues to why some get PAH and others Don't
Knowledge-focused Recruiting nowThis study is looking at people with pulmonary arterial hypertension (PAH), those with a genetic risk but no disease, and healthy individuals. Researchers aim to find molecular and physical markers that explain why some people get PAH and others stay healthy. The goal is to impro…
Sponsor: Vanderbilt University Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Scientists probe hidden links between hormones and lung disease
Knowledge-focused Recruiting nowThis study looks at how hormones and metabolism are involved in pulmonary arterial hypertension (PAH), a serious lung condition. Researchers will measure sex hormone levels, insulin resistance, and test two potential treatments—metformin and ACE-2—in small groups. The goal is to …
Sponsor: Vanderbilt University Medical Center • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:37 UTC