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Hematologic disorder
MONDO:0005570A disease involving the hematopoietic system.
Also known as: blood disease, blood disorder, disease of hematopoietic system, disease of the blood and blood-forming organs, disease or disorder of haematopoietic system, disease or disorder of hematopoietic system, disorder of haematopoietic system, disorder of hematopoietic system
8525 clinical trials for this condition and its sub-types, 176 tagged with Hematologic disorder itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Hematologic disorder
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Hematopoietic and lymphoid system neoplasm 692 trials · 6,335 incl. sub-types
9 sub-types
- Hematopoietic and lymphoid cell neoplasm 486 trials · 5,943 incl. sub-types Sub-types →
- Lymphoid hemopathy 0 trials · 4,285 incl. sub-types Sub-types →
- Myeloid hemopathy 0 trials · 1,765 incl. sub-types Sub-types →
- Bone marrow neoplasm 3 trials · 1,633 incl. sub-types Sub-types →
- Thymus neoplasm 5 trials · 240 incl. sub-types Sub-types →
- Spleen neoplasm 0 trials · 232 incl. sub-types Sub-types →
- Lymph node neoplasm 5 trials · 60 incl. sub-types Sub-types →
- STAT3-related early-onset multisystem autoimmune disease 2 trials
- Cavernous hemangioma 1 trial Sub-types →
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Leukocyte disorder 6 trials · 3,581 incl. sub-types
23 sub-types
- B-cell neoplasm 305 trials · 3,174 incl. sub-types Sub-types →
- T-cell leukemia 9 trials · 137 incl. sub-types Sub-types →
- B cell deficiency 5 trials · 86 incl. sub-types Sub-types →
- Leukopenia 6 trials · 78 incl. sub-types Sub-types →
- Dendritic cell sarcoma 0 trials · 53 incl. sub-types Sub-types →
- Eosinophil disorder 2 trials · 51 incl. sub-types Sub-types →
- Langerhans cell histiocytosis 40 trials · 41 incl. sub-types Sub-types →
- Phagocyte bactericidal dysfunction 0 trials · 37 incl. sub-types Sub-types →
- Mastocytosis 15 trials · 34 incl. sub-types Sub-types →
- Functional neutrophil defect 0 trials · 13 incl. sub-types Sub-types →
- Mast cell activation syndrome 8 trials · 9 incl. sub-types Sub-types →
- POEMS syndrome 8 trials
- Subcutaneous panniculitis-like T-cell lymphoma 8 trials
- EBV-positive T-cell lymphoproliferative disorder of childhood 3 trials · 7 incl. sub-types Sub-types →
- Thymoma type B 0 trials · 4 incl. sub-types Sub-types →
- Human granulocytic anaplasmosis 1 trial
- Pelger-Huet anomaly 0 trials
- Eosinophil peroxidase deficiency 0 trials
- Hereditary neutrophilia 0 trials
- Human monocytic ehrlichiosis 0 trials
- Leukostasis 0 trials
- Pituitary gland basophil adenoma 0 trials
- Small intestinal enteropathy-associated T-cell lymphoma 0 trials
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Bone marrow disorder 18 trials · 1,763 incl. sub-types
7 sub-types
- Bone marrow neoplasm 3 trials · 1,633 incl. sub-types Sub-types →
- Polycythemia 9 trials · 99 incl. sub-types Sub-types →
- Bone marrow failure syndrome 48 trials Sub-types →
- Osteomyelitis 43 trials · 46 incl. sub-types Sub-types →
- Fanconi anemia 29 trials · 42 incl. sub-types Sub-types →
- Drachtman Weinblatt Sitarz syndrome 0 trials
- Premature ovarian failure 15 0 trials
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Anemia 258 trials · 975 incl. sub-types
19 sub-types
- Aplastic anemia 110 trials · 411 incl. sub-types Sub-types →
- Normocytic anemia 0 trials · 180 incl. sub-types Sub-types →
- Microcytic anemia 0 trials · 130 incl. sub-types Sub-types →
- Hypochromic anemia 0 trials · 123 incl. sub-types Sub-types →
- Beta-thalassemia and related diseases 0 trials · 99 incl. sub-types Sub-types →
- Congenital anemia 0 trials · 58 incl. sub-types Sub-types →
- Anemia due to chronic disorder 34 trials
- Pure red-cell aplasia 5 trials · 24 incl. sub-types Sub-types →
- Neonatal anemia 7 trials · 23 incl. sub-types Sub-types →
- Deficiency anemia 3 trials · 16 incl. sub-types Sub-types →
- Pancytopenia 15 trials
- Anemia due to enzyme disorder 1 trial · 14 incl. sub-types Sub-types →
- Sideroblastic anemia 0 trials · 14 incl. sub-types Sub-types →
- Macrocytic anemia 0 trials · 11 incl. sub-types Sub-types →
- Hemoglobin C disease 2 trials
- Hereditary methemoglobinemia 0 trials · 1 incl. sub-types Sub-types →
- Hemoglobin D disease 0 trials
- Hemoglobin E disease 0 trials
- Hemoglobinopathy Toms River 0 trials
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Erythrocyte disorder 7 trials · 618 incl. sub-types
2 sub-types
- Hemoglobinopathy 34 trials · 446 incl. sub-types Sub-types →
- Malaria 135 trials · 170 incl. sub-types Sub-types →
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Blood coagulation disease 54 trials · 541 incl. sub-types
8 sub-types
- Inherited blood coagulation disorder 8 trials · 323 incl. sub-types Sub-types →
- Coagulation protein disease 13 trials · 274 incl. sub-types Sub-types →
- Thrombotic microangiopathy 26 trials · 151 incl. sub-types Sub-types →
- Thrombophilia 12 trials · 75 incl. sub-types Sub-types →
- Hemolytic-uremic syndrome 7 trials · 24 incl. sub-types Sub-types →
- Hemorrhagic disease of newborn 1 trial
- Marantic endocarditis 0 trials
- Prekallikrein deficiency 0 trials Sub-types →
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Hemorrhagic disease 108 trials · 510 incl. sub-types
28 sub-types
- Hemophilia A 180 trials Sub-types →
- Purpura 4 trials · 117 incl. sub-types Sub-types →
- Hemophilia B 84 trials · 91 incl. sub-types Sub-types →
- Vascular hemostatic disease 62 trials · 63 incl. sub-types Sub-types →
- Hereditary von Willebrand disease 18 trials · 29 incl. sub-types Sub-types →
- Inherited bleeding disorder, platelet-type 6 trials · 26 incl. sub-types Sub-types →
- Acquired hemophilia 2 trials · 8 incl. sub-types Sub-types →
- Congenital fibrinogen deficiency 2 trials · 6 incl. sub-types Sub-types →
- Factor VII deficiency 6 trials Sub-types →
- Congenital vitamin K-dependent coagulation factors deficiency 0 trials · 4 incl. sub-types Sub-types →
- Fetal and neonatal alloimmune thrombocytopenia 4 trials Sub-types →
- Acquired von willebrand syndrome 3 trials
- Factor X deficiency 2 trials Sub-types →
- Congenital factor XII deficiency 1 trial
- Congenital plasminogen activator inhibitor type 1 deficiency 1 trial
- East Texas bleeding disorder 0 trials
- Alpha-2-plasmin inhibitor deficiency 0 trials
- Combined deficiency of factor V and factor VIII 0 trials Sub-types →
- Congenital factor V deficiency 0 trials
- Congenital factor XI deficiency 0 trials
- Congenital factor XIII deficiency 0 trials Sub-types →
- Congenital high-molecular-weight kininogen deficiency 0 trials
- Hemophilia B leyden 0 trials
- Hemorrhagic disease due to alpha-1-antitrypsin Pittsburgh mutation 0 trials
- Inherited prekallikrein deficiency 0 trials
- Multiple sclerosis-ichthyosis-factor VIII deficiency syndrome 0 trials
- Prothrombin deficiency 0 trials Sub-types →
- Thrombomodulin-related bleeding disorder 0 trials
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Blood platelet disease 18 trials · 370 incl. sub-types
5 sub-types
- Thrombocytopenia 75 trials · 267 incl. sub-types Sub-types →
- Thrombocytosis disease 7 trials · 71 incl. sub-types Sub-types →
- Inherited bleeding disorder, platelet-type 6 trials · 26 incl. sub-types Sub-types →
- Qualitative platelet defect 6 trials
- TPM4-related platelet disorder 0 trials
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Splenic disorder 3 trials · 248 incl. sub-types
8 sub-types
- Spleen neoplasm 0 trials · 232 incl. sub-types Sub-types →
- Hypersplenism 12 trials
- Splenic sequestration 1 trial
- Congestive splenomegaly 0 trials Sub-types →
- Splenic abscess 0 trials
- Splenic infarction 0 trials
- Splenic tuberculosis 0 trials
- Wandering spleen 0 trials
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Thymus gland disorder 1 trial · 240 incl. sub-types
3 sub-types
- Thymus neoplasm 5 trials · 240 incl. sub-types Sub-types →
- Ectopic thymus 0 trials
- Thymic dysplasia 0 trials
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Autoimmune disorder of blood 0 trials · 152 incl. sub-types
2 sub-types
- Primary thrombocytopenia 27 trials · 110 incl. sub-types Sub-types →
- Autoimmune hemolytic anemia 49 trials · 72 incl. sub-types Sub-types →
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Congenital hematological disorder 1 trial · 101 incl. sub-types
21 sub-types
- Congenital anemia 0 trials · 58 incl. sub-types Sub-types →
- Constitutional neutropenia 2 trials · 28 incl. sub-types Sub-types →
- Congenital thrombotic thrombocytopenic purpura 5 trials
- Congenital vitamin K-dependent coagulation factors deficiency 0 trials · 4 incl. sub-types Sub-types →
- GNE myopathy 3 trials
- Congenital amegakaryocytic thrombocytopenia 1 3 trials
- Leukocyte adhesion deficiency type II 2 trials
- Congenital factor XII deficiency 1 trial
- Congenital plasminogen activator inhibitor type 1 deficiency 1 trial
- Thrombocytopenia-absent radius syndrome 1 trial
- Congenital agammaglobulinemia 0 trials Sub-types →
- Congenital analbuminemia 0 trials
- Congenital factor XI deficiency 0 trials
- Congenital factor XIII deficiency 0 trials Sub-types →
- Congenital progressive bone marrow failure-B-cell immunodeficiency-skeletal dysplasia syndrome 0 trials
- Congenital secondary polycythemia 0 trials Sub-types →
- Hereditary thrombocytosis with transverse limb defect 0 trials
- Hypercoagulability syndrome due to glycosylphosphatidylinositol deficiency 0 trials
- Macrothrombocytopenia-lymphedema-developmental delay-facial dysmorphism-camptodactyly syndrome 0 trials
- Radio-ulnar synostosis-amegakaryocytic thrombocytopenia syndrome 0 trials Sub-types →
- Sulfhemoglobinemia, congenital 0 trials
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Monoclonal gammopathy 24 trials · 68 incl. sub-types
3 sub-types
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Premalignant hematological system disease 3 trials · 25 incl. sub-types
2 sub-types
- Clonal hematopoiesis 10 trials · 22 incl. sub-types Sub-types →
- Atypical lymphoproliferative disorder 0 trials
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Paraneoplastic hematological syndrome 0 trials · 9 incl. sub-types
2 sub-types
- POEMS syndrome 8 trials
- Humoral hypercalcemia of malignancy 1 trial
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Parasitemia 5 trials
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Blood group incompatibility 2 trials
1 sub-type
- Rh isoimmunization 0 trials
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L-ferritin deficiency 1 trial
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Hyperamylasemia 1 trial
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Bloom syndrome 0 trials
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GATA1-Related X-Linked Cytopenia 0 trials
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Polyclonal hyperviscosity syndrome 0 trials
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Septicemic plague 0 trials
Most studied deeper sub-types
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Could bone marrow from deceased donors cure blood cancers?
Cure Not yet recruitingThis study tests whether bone marrow from deceased donors can be used to treat people with blood cancers like leukemia and lymphoma. Participants receive a transplant of cryopreserved marrow from a deceased donor or standard cells from a living donor. The goal is to see if the de…
Sponsor: Ossium Health, Inc. • Aim: Cure
Last updated Sep 12, 2026 00:00 UTC
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New stem cell filtering method could make transplants safer for kids
Disease control Not yet recruitingThis early-phase study tests a new way to do stem cell transplants for children and young adults with blood diseases. Doctors will take stem cells from a family member or closely matched unrelated donor, filter out certain immune cells using a special machine, and then give them …
Phase 1 • Sponsor: University of Wisconsin, Madison • Aim: Disease control
Last updated Sep 04, 2026 00:00 UTC
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Experimental drug targets bone marrow failure
Disease control Not yet recruitingThis study tests an experimental drug called dibotatug (DR-01) in adults with bone marrow failure syndromes, including severe aplastic anemia. The goal is to see if the drug is safe and can improve blood cell counts. Participants receive dibotatug by IV infusion, and researchers …
Phase 1/2 • Sponsor: Dren Bio • Aim: Disease control
Last updated Jul 26, 2026 00:00 UTC
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Double-Pronged immune cells take aim at stubborn blood cancers
Disease control Not yet recruitingThis phase 1 trial tests an experimental therapy called 20-19 Tan BB06z CAR-T for people with certain blood cancers (like lymphoma or leukemia) that have come back or not responded to treatment. The therapy involves taking a patient's own immune T cells, genetically modifying the…
Phase 1 • Sponsor: Roswell Park Cancer Institute • Aim: Disease control
Last updated Jul 17, 2026 00:00 UTC
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New hope for blood cancer patients with tough fungal infections
Disease control Not yet recruitingThis study looks at whether the drug amphotericin B can treat serious fungal infections that break through in people with blood cancers who are already taking antifungal prevention. About 15 adults will receive the drug for 4-6 weeks and be closely monitored. The goal is to see h…
Sponsor: Peking University People's Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:25 UTC
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New CAR-T therapy targets antibodies blocking Life-Saving transplants
Disease control Not yet recruitingThis early-stage study tests a new treatment using special immune cells (CAR-T cells) designed to reduce harmful antibodies that can prevent or damage bone marrow transplants. About 18 people with blood diseases who have these antibodies will receive the cells in increasing doses…
Phase 1/2 • Sponsor: Chang Yingjun • Aim: Disease control
Last updated Jun 27, 2026 09:10 UTC
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New drug aims to fix Immunotherapy's blood problems in lung cancer
Disease control Not yet recruitingThis phase 2 trial tests the drug golidocitinib in 16 people with advanced lung cancer who have severe blood problems caused by immunotherapy. The goal is to see if the drug can safely improve blood counts and reduce symptoms. Participants take the drug until their blood levels r…
Phase 2 • Sponsor: The First Affiliated Hospital of Guangzhou Medical University • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
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Could virtual reality help patients recover faster from cell therapy?
Symptom relief Not yet recruitingThis study tests whether using an immersive virtual reality headset during exercise can improve motivation, adherence, and emotional well-being in adults undergoing cell therapy or stem cell transplant. Participants follow a therapeutic exercise program with or without VR. The tr…
Sponsor: Fundacin Biomedica Galicia Sur • Aim: Symptom relief
Last updated Sep 04, 2026 00:00 UTC
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Blood test could predict bleeding risk in cancer patients
Knowledge-focused Not yet recruitingThis study aims to create a score that uses a special blood test to predict bleeding risk in people with blood cancers and very low platelet counts. Researchers will take an extra blood sample from 410 participants and analyze it with viscoelastometric tests. The goal is to ident…
Sponsor: Centre Hospitalier Annecy Genevois • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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French study to probe alternative medicine use in blood cancer patients
Knowledge-focused Not yet recruitingThis study looks at how people with blood cancers (like leukemia, lymphoma, or myeloma) in France use complementary and alternative medicines (CAM), such as acupuncture or herbal remedies. Researchers will survey 85 patients and interview some to understand why they use these the…
Sponsor: University Hospital, Limoges • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Hidden parasites may worsen blood diseases, new study warns
Knowledge-focused Not yet recruitingThis study will check how common parasitic infections are in 285 people with blood disorders, like anemia or blood cancers, at Assiut University hospitals in Egypt. Researchers will test for Toxoplasma and other parasites. The goal is to understand if routine screening could help…
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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Massive study to uncover hidden link between blood mutations and immune disorders
Knowledge-focused Not yet recruitingThis study will follow 5,000 adults with immune system problems to see if certain blood cell mutations (called clonal hematopoiesis) are linked to their condition. Researchers will track new cases of immune-related diseases over time. No treatments or drugs are tested—this is pur…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC