Heavy metal poisoning
MONDO:0023305Heavy metal poisoning refers to when excessive exposure to a heavy metal affects the normal function of the body. Examples of heavy metals that can cause toxicity include lead, mercury, arsenic, cadmium, and chromium. Exposure may occur through the diet, from medications, from the environment, or in the course of work or play. Heavy metals can enter the body through the skin, or by inhalation or ingestion. Toxicity can result from sudden, severe exposure, or from chronic exposure over time. Symptoms can vary depending on the metal involved, the amount absorbed, and the age of the person exposed. For example, young children are more susceptible to the effects of lead exposure because they absorb more compared with adults and their brains are still developing. Nausea, vomiting, diarrhea, and abdominal pain are common symptoms of acute metal ingestion. Chronic exposure may cause various symptoms resulting from damage to body organs, and may increase the risk of cancer. Treatment depends on the circumstances of the exposure.
Also known as: heavy metal poisoning, toxic effect of heavy metal, chronic heavy metal poisoning, heavy metal toxicity, heavy metal toxicosis
10 clinical trials for this condition and its sub-types.
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Broader categories
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Could an iron scavenger slow ALS?
Disease control CompletedThis study tested whether deferiprone, a drug that removes excess iron, could safely slow the progression of ALS. Researchers gave the drug to 23 adults with ALS for several months. The goal was to see if reducing iron buildup in the brain might protect nerve cells and delay wors…
Phase: PHASE2 • Sponsor: University Hospital, Lille • Aim: Disease control
Last updated Jun 27, 2026 09:07 UTC
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Simple blood tests may spot liver damage in thalassemia kids
Diagnosis CompletedThis study looked at 100 children with beta-thalassemia major and iron overload to see if simple blood tests (ferritin and hepcidin) can detect liver scarring (fibrosis) as accurately as other non-invasive methods. Researchers measured these blood markers and compared them to ult…
Sponsor: Tanta University • Aim: Diagnosis
Last updated Jun 26, 2026 14:15 UTC
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Vaping study reveals hidden metals in young users' saliva
Knowledge-focused CompletedThis study looked at 58 young adults aged 18-29 who regularly use e-cigarettes. Researchers measured heavy metals in their saliva and tested their lung function before and after a 30-minute vaping session. The goal was to understand how vaping exposes the body to metals and affec…
Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC
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Lab study tests Iron-Binding drug on Parkinson's and ALS cells
Knowledge-focused CompletedThis completed study looked at how the drug deferiprone affects blood cells from 90 people with Parkinson's disease, ALS, or healthy volunteers. Researchers measured markers of oxidative stress and iron levels in the lab. The goal was to better understand these diseases, not to t…
Phase: NA • Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC