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Goldberg-Shprintzen syndrome

MONDO:0012280

A multiple malformation syndrome characterized by Hirschprung megacolon with microcephaly, hypertelorism, submucous cleft palate, short stature and learning disability.

Also known as: GOSHS, Goldberg-Shprintzen megacolon syndrome, Goldberg-Shprintzen syndrome, megacolon-microcephaly syndrome

3 clinical trials for this condition and its sub-types.

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Broader categories

Disease (680) Hereditary disease (176) Digestive system disorder (160) Intestinal disorder (66) Syndromic disease (25) Human disease (14) Intestinal motility disease (9) Developmental defect during embryogenesis (8) Disease of genetic or genomic mechanism (2) Multiple congenital anomalies/dysmorphic syndrome (1)
Trials to join now! 2 Completed 1
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  • Kids' laxative study reveals how body handles the drug

    Knowledge-focused Completed

    This study measured levels of the laxative PEG 3350 and its breakdown products in the blood and urine of 158 children who were already taking it, compared to children not taking it. The goal was simply to learn how the body processes this medicine, not to change any treatments. R…

    Sponsor: Children's Hospital of Philadelphia • Aim: Knowledge-focused

    Last updated Jun 27, 2026 07:56 UTC

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