Filoviridae infectious disease

This study evaluates a new diagnostic test called DECIPHER bioassay for detecting Ebola virus. Researchers will use stored blood and cheek swab samples from patients in the Democratic Republic of the Congo to see how well the new test compares to the standard lab method. The goal…

This study evaluates two new diagnostic tests (FORTIFIEDx and DECIPHER) for detecting Ebola and Lassa viruses. Researchers will use stored blood and cheek swab samples from patients in Guinea to see how well these tests compare to the standard PCR method. The goal is to determine…

This study tests whether giving the Ervebo Ebola vaccine together with the antibody drug Inmazeb still works to protect people who may have been exposed to Ebola. The vaccine alone takes time to work, while antibodies act fast but might interfere with the vaccine. Researchers wil…

This study tests whether giving a vaccine plus an antibody drug right after high-risk Ebola contact can prevent the disease better than the vaccine alone. About 160 people who have had close contact with an Ebola patient (like touching body fluids or a dead body) will be randomly…