Familial clubfoot with or without associated lower limb anomalies
MONDO:0016046Familial clubfoot with or without associated lower limb anomalies is a rare congenital limb malformation syndrome characterized by malalignment of the bones and joints of the foot and ankle, with presence of forefoot and midfoot adductus, hindfoot varus, and ankle equinus, presenting as rigid inward turning of the foot towards the midline, in various members of a single family. Hypoplasia of lower leg muscles is a frequently associated finding. Patients may present with other low-limb malformations, such as patellar hypoplasia, oblique talus, tibial hemimelia, and polydactyly.
23 clinical trials for this condition and its sub-types.
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Broader categories
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Which surgery fixes clubfoot best? new trial aims to find out
Disease control Not yet recruitingThis trial compares two surgical procedures for children aged 5 to 10 with relapsed clubfoot and a specific foot deformity called metatarsal adductus. One surgery involves cutting and realigning the midfoot bones, followed by 6 weeks in a cast. The other uses a small plate to gui…
Phase: NA • Sponsor: Assiut University • Aim: Disease control
Last updated Jun 27, 2026 12:03 UTC
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Shoes that could change how stroke survivors walk
Symptom relief Not yet recruitingThis study looks at whether custom-made shoes can improve walking quality in people who have had a stroke and still have trouble walking due to muscle tightness and foot dragging. About 58 adults who had a stroke at least 6 months ago will wear adapted shoes and be tested on how …
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Symptom relief
Last updated Jun 27, 2026 09:04 UTC
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Ultrasound maps hidden nerves in clubfoot babies to make surgery safer
Knowledge-focused Not yet recruitingThis study will use ultrasound to measure the distance between the Achilles tendon and nearby nerves and blood vessels in both feet of 40 infants with unilateral clubfoot. By comparing the clubfoot to the normal foot, researchers hope to give surgeons better guidance to avoid acc…
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC